Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 12/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 10/20 | 0.55 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.55 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19718448 | 0.94 | KMT2A (0.55) | L3MBTL3L3MBTL1MBTD1TP53BP1KMT2A | |
| SCHEMBL10263761 | 0.87 | L3MBTL3 (0.73) | L3MBTL3L3MBTL1MBTD1TP53BP1KMT2A | |
| SCHEMBL12845378 | 0.87 | KMT2A (0.56) | L3MBTL3L3MBTL1MBTD1TP53BP1KMT2A | |
| SCHEMBL12826643 | 0.84 | L3MBTL3 (0.60) | L3MBTL3L3MBTL1MBTD1TP53BP1KMT2A | |
| SCHEMBL178275 | 0.83 | ALDH1A1 (0.63) | L3MBTL1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL12127969 | 0.83 | KMT2A (0.52) | L3MBTL3L3MBTL1MBTD1TP53BP1KMT2A | |
| SCHEMBL10263756 | 0.83 | KMT2A (0.52) | L3MBTL3L3MBTL1MBTD1TP53BP1KMT2A | |
| SCHEMBL12127756 | 0.83 | KMT2A (0.52) | L3MBTL3L3MBTL1MBTD1TP53BP1KMT2A | |
| SCHEMBL13616253 | 0.82 | L3MBTL3 (0.59) | L3MBTL3L3MBTL1MBTD1TP53BP1KMT2A | |
| SCHEMBL156422 | 0.81 | ALDH1A1 (0.68) | L3MBTL3L3MBTL1MBTD1TP53BP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3838898-B1 | ISOINDOLIN-1-ONE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AS AN EFFECTIVE COMPONENT FOR PREVENTING OR TREATING CANCER | KOREA RES INST CHEMICAL TECH (KR) | 2023-06-07 | — | — | EP | disclosed |
| EP-3838898-A1 | ISOINDOLIN-1-ON DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT FOR PREVENTING OR TREATING CANCER | Korea Research Institute of Chemical Technology (KR) | 2021-06-23 | — | — | EP | disclosed |