Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.45 |
| ▸ | CCKAR | P32238 | 3/20 | 0.41 |
| ▸ | CCKBR | P32239 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23544194 | 0.90 | GLP1R (0.62) | GLP1RFOLH1NOD1 | |
| SCHEMBL26059901 | 0.88 | GLP1R (0.68) | GLP1RFOLH1NOD1CCKARCCKBR | |
| SCHEMBL21572001 | 0.88 | GLP1R (0.59) | GLP1RFOLH1NOD1 | |
| SCHEMBL24494709 | 0.87 | GLP1R (0.67) | GLP1RFOLH1NOD1CCKARCCKBR | |
| SCHEMBL21242717 | 0.87 | GLP1R (0.67) | GLP1RFOLH1CCKARCCKBR | |
| SCHEMBL12806524 | 0.86 | GLP1R (0.64) | GLP1RFOLH1NOD1 | |
| SCHEMBL15507705 | 0.86 | GLP1R (0.64) | GLP1RFOLH1NOD1 | |
| SCHEMBL14117977 | 0.86 | GLP1R (0.67) | GLP1RFOLH1NOD1 | |
| SCHEMBL15507496 | 0.86 | GLP1R (0.64) | GLP1RFOLH1NOD1 | |
| SCHEMBL13146937 | 0.86 | GLP1R (0.64) | GLP1RFOLH1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3447067-B1 | GLP-1R/GCGR DUAL TARGET AGONIST POLYPEPTIDE FOR TREATING NON-ALCOHOLIC FATTY LIVER DISEASES | SHENZHEN TURIER BIOTECH CO LTD (CN) | 2021-06-23 | — | — | EP | disclosed |