SCHEMBL12806524

SCHEMBL12806524

NN[C@@H](CCCCNC(=O)CC[C@H](NC(=O)CCOCCOCCOCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.64
▸ FOLH1 Q04609 7/20 0.51
▸ GNPAT O15228 1/20 0.51
▸ NOD1 Q9Y239 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12806475 1.00 GLP1R (0.64) GLP1RFOLH1GNPATNOD1
SCHEMBL12806517 1.00 GLP1R (0.64) GLP1RFOLH1GNPATNOD1
SCHEMBL12806523 1.00 GLP1R (0.64) GLP1RFOLH1GNPATNOD1
SCHEMBL15507705 1.00 GLP1R (0.64) GLP1RFOLH1GNPATNOD1
SCHEMBL15507496 1.00 GLP1R (0.64) GLP1RFOLH1GNPATNOD1
SCHEMBL12806418 1.00 GLP1R (0.64) GLP1RFOLH1GNPATNOD1
SCHEMBL12806522 1.00 GLP1R (0.64) GLP1RFOLH1GNPATNOD1
SCHEMBL24486694 0.94 GLP1R (0.70) GLP1RFOLH1GNPATNOD1
SCHEMBL8248469 0.94 GLP1R (0.70) GLP1RFOLH1GNPATNOD1
SCHEMBL12806481 0.94 GLP1R (0.70) GLP1RFOLH1GNPATNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9150633-B2 Insulin analogues with an acyl and alkylene glycol moiety NOVO NORDISK A/S (DK) 2015-10-06 — — US disclosed
US-20150210748-A1 PROTEASE STABILIZED ACYLATED INSULIN ANALOGUES NOVO NORDISK AS (DK) 2015-07-30 — — US disclosed
US-20110098440-A1 Insulin Analogues with an Acyl and Alkylene Glycol Moiety NOVO NORDISK A/S (DK) 2011-04-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098440-A1 Insulin Analogues with an Acyl and Alkylene Glycol Moiety IAPP, INSR, IGF1R GLP1R 7/4885FOLH1 1261/4885GNPAT 2340/4885
US-20150210748-A1 PROTEASE STABILIZED ACYLATED INSULIN ANALOGUES IAPP, IDE, LIPE GLP1R 54/4885FOLH1 524/4885GNPAT 1212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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