Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2756366 | 0.85 | RAPGEF4 (0.57) | RAPGEF4LMNAALDH1A1FFAR4MAPT | |
| SCHEMBL5845349 | 0.81 | RAPGEF4 (0.52) | RAPGEF4LMNAALDH1A1FFAR4MAPT | |
| SCHEMBL12963494 | 0.79 | RAPGEF4 (0.50) | RAPGEF4LMNAALDH1A1FFAR4TSHR | |
| SCHEMBL2335362 | 0.79 | RAPGEF4 (0.50) | RAPGEF4LMNAALDH1A1MAPTTDP1 | |
| SCHEMBL812880 | 0.79 | RAPGEF4 (0.50) | RAPGEF4LMNAALDH1A1FFAR4MAPT | |
| SCHEMBL13917945 | 0.77 | RAPGEF4 (0.48) | RAPGEF4LMNAALDH1A1 | |
| SCHEMBL814154 | 0.77 | RAPGEF4 (0.48) | RAPGEF4LMNAALDH1A1FFAR4MAPT | |
| SCHEMBL814620 | 0.77 | RAPGEF4 (0.48) | RAPGEF4LMNAALDH1A1FFAR4MAPT | |
| SCHEMBL813197 | 0.77 | RAPGEF4 (0.48) | RAPGEF4LMNAALDH1A1FFAR4MAPT | |
| SCHEMBL1812889 | 0.77 | RAPGEF4 (0.48) | RAPGEF4LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7999039-B2 | Catalytic polymerization of olefinic monomers in the presence of a high molecular weight catalyst and a low molecular weight catalyst in a polymerization reactor system; high melt strength | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-08-16 | — | — | US | disclosed |