SCHEMBL812880

SCHEMBL812880

Cc1cc(C)c(NCCNCCNc2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 13/20 0.50
LMNA P02545 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 2/20 0.36
GAA P10253 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HTT P42858 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL813197 0.98 RAPGEF4 (0.48) RAPGEF4LMNAALDH1A1MAPTGAA
SCHEMBL814154 0.98 RAPGEF4 (0.48) RAPGEF4LMNAALDH1A1MAPTGAA
SCHEMBL816160 0.98 RAPGEF4 (0.48) RAPGEF4LMNAALDH1A1MAPTGAA
SCHEMBL814620 0.98 RAPGEF4 (0.48) RAPGEF4LMNAALDH1A1MAPTGAA
SCHEMBL814425 0.98 RAPGEF4 (0.48) RAPGEF4LMNAALDH1A1MAPTGAA
Hydrochloric Acid SCHEMBL812732 0.96 RAPGEF4 (0.46) RAPGEF4LMNAALDH1A1MAPTGAA
Hydrochloric Acid SCHEMBL814581 0.96 RAPGEF4 (0.46) RAPGEF4LMNAALDH1A1MAPTGAA
Hydrochloric Acid SCHEMBL815781 0.96 RAPGEF4 (0.46) RAPGEF4LMNAALDH1A1MAPTGAA
Hydrochloric Acid SCHEMBL814671 0.96 RAPGEF4 (0.46) RAPGEF4LMNAALDH1A1MAPTGAA
Hydrochloric Acid SCHEMBL813594 0.96 RAPGEF4 (0.46) RAPGEF4LMNAALDH1A1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2931421-B1 CATALYST SYSTEM FOR THE PREPARATION OF POLYOLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2019-06-26 EP disclosed
US-9458271-B2 Catalyst system for the preparation of polyolefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2016-10-04 US disclosed
US-9458271-B2 Catalyst system for the preparation of polyolefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2016-10-04 US disclosed
US-20150329657-A1 CATALYST SYSTEM FOR THE PREPARATION OF POLYOLEFINS Basell Poliolefine Italia, s.r.l. (IT) 2015-11-19 US disclosed
US-20150329657-A1 CATALYST SYSTEM FOR THE PREPARATION OF POLYOLEFINS Basell Poliolefine Italia, s.r.l. (IT) 2015-11-19 US disclosed
WO-2014090554-A1 CATALYST SYSTEM FOR THE PREPARATION OF POLYOLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2014-06-19 WO disclosed
EP-2743000-A1 Catalyst system for the preparation of polyolefins Basell Poliolefine Italia S.r.l. (IT) 2014-06-18 EP disclosed
US-8058372-B2 Catalyst composition II EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-11-15 US disclosed
US-20080319147-A1 Catalyst Composition II EXXONMOBIL CHEMICAL PATENTS INC. 2008-12-25 US disclosed
US-7371803-B2 Catalyst composition II EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-05-13 US disclosed
US-20070066776-A1 Catalyst composition II SOLAN GREGORY A 2007-03-22 US disclosed
US-7189791-B2 Catalyst composition II EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-03-13 US disclosed
EP-1641842-A2 POLYMERIZATION AND OLIGOMERIZATION CATALYST WITH TRIDENTATE OR TETRADENTATE LIGAND Exxonmobil Chemical Patents Inc. (US) 2006-04-05 EP disclosed
US-20040266961-A1 Catalyst composition II EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-30 US disclosed
WO-2004106390-A2 POLYMERIZATION AND OLIGOMERIZATION CATALYST WITH TRIDENTATE OR TETRADENTATE LIGAND EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-12-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040266961-A1 Catalyst composition II MLX, CBX2, BMX RAPGEF4 4437/4885LMNA 25/4885ALDH1A1 4593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.