Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MYC | P01106 | 9/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16188020 | 0.78 | KDM4E (0.52) | KDM4EGAAMEN1USP2TP53 | |
| SCHEMBL13170405 | 0.75 | KDM4E (0.60) | KDM4EGAAMEN1USP2TP53 | |
| SCHEMBL11073745 | 0.74 | IDO1 (0.52) | KDM4EGAAMEN1USP2TP53 | |
| SCHEMBL8544900 | 0.73 | POLB (0.65) | KDM4EGAAMEN1KMT2APOLB | |
| SCHEMBL13893345 | 0.71 | KDM4E (0.56) | KDM4EGAAMEN1USP2TP53 | |
| SCHEMBL2976296 | 0.71 | KDM4E (1.00) | KDM4EGAAMEN1USP2TP53 | |
| SCHEMBL3982909 | 0.71 | KDM4E (0.56) | KDM4EGAAMEN1USP2TP53 | |
| SCHEMBL21354472 | 0.71 | MAPT (0.64) | KDM4EGAAMEN1HTTKMT2A | |
| SCHEMBL29280164 | 0.71 | ALDH1A1 (0.52) | KDM4EGAAMEN1USP2HTT | |
| SCHEMBL13856248 | 0.70 | MYC (1.00) | MYCNR4A1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2528979-A1 | EPOXY-BASED PRIMER COMPOSITIONS | Hempel A/S (DK) | 2012-12-05 | — | — | EP | disclosed |
| WO-2011092278-A1 | EPOXY-BASED PRIMER COMPOSITIONS | HEMPEL A/S (DK) | 2011-08-04 | — | — | WO | disclosed |
| US-4016283-A | ADRENERGIC BLOCKING AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |
| US-3984436-A | BLOCKERS OF ADRENERGIC B-RECEPTORS | CIBA-GEIGY CORPORATION (US) | 1976-10-05 | — | — | US | disclosed |