Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MYC | P01106 | 8/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19469834 | 0.82 | KDM4E (0.47) | KDM4EGAAMEN1KMT2AUSP2 | |
| SCHEMBL13170405 | 0.75 | KDM4E (0.60) | KDM4EGAAMEN1KMT2AUSP2 | |
| SCHEMBL20600365 | 0.72 | GAA (0.38) | KDM4EGAAMEN1KMT2AUSP2 | |
| SCHEMBL2976296 | 0.71 | KDM4E (1.00) | KDM4EGAAMEN1KMT2AUSP2 | |
| SCHEMBL13893345 | 0.71 | KDM4E (0.56) | KDM4EGAAMEN1KMT2AUSP2 | |
| SCHEMBL2354485 | 0.71 | KDM4E (0.56) | KDM4EGAAMEN1KMT2AUSP2 | |
| SCHEMBL31198223 | 0.70 | BCHE (0.41) | KDM4EGAAMEN1KMT2ATP53 | |
| SCHEMBL12727350 | 0.70 | MYC (0.56) | KDM4EGAAMEN1KMT2AUSP2 | |
| SCHEMBL4882091 | 0.70 | MYC (0.54) | KDM4EGAAMEN1KMT2AUSP2 | |
| SCHEMBL782631 | 0.70 | ALDH1A1 (0.50) | KDM4EGSK3AGSK3BALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |