SCHEMBL235454

SCHEMBL235454

C#CCCOC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5323835 0.83
SCHEMBL14762260 0.83 CA2 (0.34)
SCHEMBL233981 0.81
SCHEMBL234987 0.79
SCHEMBL3686847 0.77
SCHEMBL1015444 0.77
SCHEMBL26908726 0.77 ALDH1A1 (0.39)
SCHEMBL1018160 0.77 ALDH1A1 (0.39)
SCHEMBL1453695 0.77 ALDH1A1 (0.39)
SCHEMBL1453240 0.77 ALDH1A1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0886507-B2 MONOMERIC COMPOSITIONS EFFECTIVE AS WOUND CLOSURE DEVICES ETHICON INC (US) 2013-03-06 EP claimed
EP-0827423-B1 FUNCTIONALIZED CHAIN EXTENDED INITIATORS FOR ANIONIC POLYMERIZATION FMC CORP (US) 2007-12-12 EP claimed
EP-0886507-B1 MONOMERIC COMPOSITIONS EFFECTIVE AS WOUND CLOSURE DEVICES CLOSURE MEDICAL CORP (US) 2007-09-26 EP claimed
EP-0525568-B1 N-Alkylated 1,4-dihydropyridine carboxylicacid ester derivatives BAYER AG (DE) 1995-05-10 EP claimed
JP-61009406-A None JP disclosed
WO-2025106949-A1 WRN INHIBITORS RADD PHARMACEUTICALS, INC. (US) 2025-05-22 WO disclosed
WO-2025098515-A1 HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF DANATLAS PHARMACEUTICALS CO., LTD. (CN) 2025-05-15 WO disclosed
EP-4392415-A1 SUBSTITUTED AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS Yuhan Corporation (KR) 2024-07-03 EP disclosed
WO-2024129763-A1 MODULATORS OF TNF-α ACTIVITY FORWARD THERAPEUTICS, INC. (US) 2024-06-20 WO disclosed
US-20240190821-A1 SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL)BENZENESULFONAMIDES AND USES THEREOF TRIANA BIOMEDICINES INC (US) 2024-06-13 US disclosed
US-20240182481-A1 PYRROLO[3,2-D]PYRIMIDINE COMPOUNDS AND METHODS OF USE IN THE TREATMENT OF CANCER TANGO THERAPEUTICS, INC. 2024-06-06 US disclosed
US-11981658-B2 Substituted aminopyridine compounds as EGFR inhibitors YUHAN CORPORATION (KR) 2024-05-14 US disclosed
US-5248693-A Antiallergens, antiinflammatory agents CIBA-GEIGY CORPORATION (US) 1993-09-28 US disclosed
US-5157029-A Insecticides, miticides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1992-10-20 US disclosed
US-5116862-A Acetylenic trithiabicyclo(2.2.2)octanes THE WELLCOME FOUNDATION LIMITED (GB) 1992-05-26 US disclosed
US-5057508-A Bicyclo(2-2-1)octanes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1991-10-15 US disclosed
US-4965257-A INSECTICIDES, ACARICIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1990-10-23 US disclosed
EP-0112261-B1 PROCESS FOR THE OXIDATION OF ALCOHOLS TO THEIR CORRESPONDING CARBONYL COMPOUNDS RHONE-POULENC S.A. (FR) 1987-05-20 EP disclosed
JP-S619406-A PRODUCTION OF POLYOLEFIN TOKUYAMA SODA CO LTD 1986-01-17 JP disclosed
US-4417038-A WITH FREE RADICAL CATALYST BASF AKTIENGESELLSCHAFT (DE) 1983-11-22 US disclosed