SCHEMBL235456

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL232937	0.96	HTR2C (0.47)	HTR2CHTR2BKDM4EALDH1A1CYP1A2
	SCHEMBL236614	0.91	ASIC3 (0.45)	HTR2CHTR2BASIC3HRH3DRD2
	Trifluoroacetic Acid SCHEMBL611293	0.89	HTR2C (0.44)	HTR2CHTR2BKDM4EALDH1A1CYP1A2
	SCHEMBL235578	0.86	KCNH2 (0.43)	HTR2CHTR2BHRH3FFAR1
	SCHEMBL232872	0.85	TAAR1 (0.40)	HTR2CHTR2BALDH1A1CYP1A2CYP3A4
	SCHEMBL3175981	0.84	KCNH2 (0.46)	HRH3FFAR1
	SCHEMBL234348	0.84	HRH3 (0.43)	HRH3FFAR1
	Hydrochloric Acid SCHEMBL614043	0.83	HRH3 (0.42)	HTR2CHTR2BHRH3FFAR1
	SCHEMBL233921	0.82	MAOA (0.49)	CYP1A2CYP3A4CYP2C9CYP2C19FFAR1
	SCHEMBL234335	0.82	HRH3 (0.50)	HRH3TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.