Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WIZ | O95785 | 6/20 | 0.75 |
| ▸ | IKZF2 | Q9UKS7 | 12/20 | 0.65 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23532847 | 1.00 | WIZ (0.75) | WIZIKZF2CRBN | |
| SCHEMBL23532852 | 1.00 | WIZ (0.75) | WIZIKZF2CRBN | |
| SCHEMBL23533145 | 0.90 | WIZ (0.78) | WIZIKZF2CRBN | |
| SCHEMBL23533148 | 0.90 | WIZ (0.78) | WIZIKZF2CRBN | |
| SCHEMBL23533166 | 0.90 | WIZ (0.80) | WIZIKZF2CRBN | |
| SCHEMBL23533113 | 0.90 | WIZ (0.80) | WIZIKZF2CRBN | |
| SCHEMBL23533111 | 0.90 | WIZ (0.80) | WIZIKZF2CRBN | |
| SCHEMBL23533172 | 0.88 | WIZ (0.79) | WIZIKZF2CRBN | |
| SCHEMBL23533483 | 0.88 | WIZ (0.77) | WIZIKZF2CRBN | |
| SCHEMBL23533484 | 0.88 | WIZ (0.77) | WIZIKZF2CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11566022-B2 | 3-(5-methoxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | NOVARTIS AG (CH) | 2023-01-31 | — | — | US | disclosed |
| US-20220402904-A1 | 3-(5-methoxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione Derivatives and Uses thereof | NOVARTIS AG (CH) | 2022-12-22 | — | — | US | disclosed |
| WO-2021124172-A1 | 3-(5-METHOXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2021-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11566022-B2 | 3-(5-methoxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | HBZ, ZFX, HBG1 | WIZ 6/4885IKZF2 7/4885CRBN 679/4885 |
| US-20220402904-A1 | 3-(5-methoxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione Derivatives and Uses thereof | HBZ, ZFX, HBG1 | WIZ 6/4885IKZF2 7/4885CRBN 618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.