Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15536247 | 0.81 | SCN9A (0.33) | NPSR1MAPTMMP1SCN9A | |
| SCHEMBL1809492 | 0.80 | NPSR1 (0.32) | NPSR1MAPTMMP1SCN9A | |
| SCHEMBL1814156 | 0.80 | NPSR1 (0.32) | NPSR1MAPTMMP1SCN9A | |
| SCHEMBL1814154 | 0.80 | NPSR1 (0.32) | NPSR1MAPTMMP1SCN9A | |
| Hydrochloric Acid SCHEMBL1812447 | 0.79 | NPSR1 (0.31) | NPSR1MAPTMMP1 | |
| Hydrochloric Acid SCHEMBL1812451 | 0.79 | NPSR1 (0.31) | NPSR1MAPTMMP1 | |
| Hydrochloric Acid SCHEMBL1812449 | 0.79 | NPSR1 (0.31) | NPSR1MAPTMMP1 | |
| SCHEMBL7651820 | 0.77 | — | — | |
| SCHEMBL18208987 | 0.77 | NPSR1 (0.34) | NPSR1MAPT | |
| SCHEMBL28540820 | 0.77 | NPSR1 (0.34) | NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11613532-B2 | Compounds active towards nuclear receptors | NUEVOLUTION A/S (DK) | 2023-03-28 | — | — | US | disclosed |
| EP-4126875-A1 | COMPOUNDS ACTIVE TOWARDS NUCLEAR RECEPTORS | Nuevolution A/S (DK) | 2023-02-08 | — | — | EP | disclosed |
| US-20220098182-A1 | COMPOUNDS ACTIVE TOWARDS NUCLEAR RECEPTORS | NUEVOLUTION A/S (DK) | 2022-03-31 | — | — | US | disclosed |
| WO-2021198956-A1 | COMPOUNDS ACTIVE TOWARDS NUCLEAR RECEPTORS | NUEVOLUTION A/S (DK) | 2021-10-07 | — | — | WO | disclosed |
| WO-2021198956-A1 | COMPOUNDS ACTIVE TOWARDS NUCLEAR RECEPTORS | NUEVOLUTION A/S (DK) | 2021-10-07 | — | — | WO | disclosed |
| US-20210188775-A1 | CARBOXAMIDE AND SULFONAMIDE DERIVATIVES USEFUL AS TEAD MODULATORS | GENENTECH, INC. (US) | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220098182-A1 | COMPOUNDS ACTIVE TOWARDS NUCLEAR RECEPTORS | NCOA1, NR1H2, NCOA3 | NPSR1 209/4885MAPT 3143/4885MMP1 4289/4885 |
| US-11613532-B2 | Compounds active towards nuclear receptors | NCOA1, NR1H2, NCOA3 | NPSR1 209/4885MAPT 3143/4885MMP1 4289/4885 |
| US-20210188775-A1 | CARBOXAMIDE AND SULFONAMIDE DERIVATIVES USEFUL AS TEAD MODULATORS | TEAD2, TEAD1, SULT2A1 | NPSR1 2440/4885MAPT 2066/4885MMP1 4718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.