Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 18/20 | 0.63 |
| ▸ | CCNE1 | P24864 | 15/20 | 0.63 |
| ▸ | CDK1 | P06493 | 3/20 | 0.63 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.63 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | CDK9 | P50750 | 3/20 | 0.54 |
| ▸ | CCNE2 | O96020 | 13/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 13/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 13/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.48 |
| ▸ | CDK7 | P50613 | 1/20 | 0.48 |
| ▸ | CCNH | P51946 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23547290 | 0.80 | CDK2 (0.45) | CDK2CCNE1CDK1CCNB1CDK9 | |
| SCHEMBL30822737 | 0.76 | CLK1 (0.58) | CDK2CCNE1CDK1CCNB1FLT3 | |
| SCHEMBL30822750 | 0.75 | FLT3 (0.57) | CDK2CCNE1CDK1CCNB1FLT3 | |
| SCHEMBL6824057 | 0.74 | FLT3 (0.58) | CDK2CCNE1CDK1CCNB1FLT3 | |
| SCHEMBL6824059 | 0.74 | FLT3 (0.58) | CDK2CCNE1CDK1CCNB1FLT3 | |
| SCHEMBL26772811 | 0.74 | CDK2 (0.61) | CDK2CCNE1CDK1CCNB1FLT3 | |
| Hydrochloric Acid SCHEMBL6817986 | 0.74 | FLT3 (0.57) | CDK2CCNE1CDK1CCNB1FLT3 | |
| Hydrochloric Acid SCHEMBL6817990 | 0.74 | FLT3 (0.57) | CDK2CCNE1CDK1CCNB1FLT3 | |
| SCHEMBL14431244 | 0.73 | CDK2 (0.50) | CDK2CCNE1CDK1CCNB1CCNE2 | |
| SCHEMBL14620256 | 0.73 | CDK2 (0.50) | CDK2CCNE1CDK1CCNB1CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021121390-A1 | HETEROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF AND APPLICATION THEREOF | 苏州信诺维医药科技股份有限公司 | 2021-06-24 | — | — | WO | disclosed |