Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | DBH | P09172 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30662204 | 1.00 | PKM (0.60) | PKMHTTLMNASMN1; SMN2ERN1 | |
| SCHEMBL5962841 | 0.87 | PKM (0.58) | PKMHTTLMNASMN1; SMN2ERN1 | |
| SCHEMBL10741618 | 0.84 | PKM (0.58) | PKMHTTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL23290095 | 0.82 | PKM (0.65) | PKMHTTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL28520723 | 0.79 | PKM (0.57) | PKMHTTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL18719476 | 0.78 | PKM (0.55) | PKMHTTLMNASMN1; SMN2ERN1 | |
| SCHEMBL9314162 | 0.76 | ERN1 (0.60) | PKMLMNAERN1KDM4ETDP1 | |
| SCHEMBL9348410 | 0.76 | PKM (0.55) | PKMHTTSMN1; SMN2ERN1L3MBTL1 | |
| SCHEMBL12082273 | 0.75 | SMN1; SMN2 (0.48) | PKMHTTLMNASMN1; SMN2ERN1 | |
| SCHEMBL14495072 | 0.75 | KDM4E (0.51) | PKMHTTLMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814319-B9 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2025-01-01 | — | — | EP | disclosed |
| EP-3814319-B1 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2024-08-14 | — | — | EP | disclosed |
| US-11970431-B2 | Polymerizable absorbers of UV and high energy visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2024-04-30 | — | — | US | disclosed |
| CN-112334444-B | Polymerizable absorbers for UV and high energy visible light | 强生视力健公司 | 2023-11-21 | — | — | CN | disclosed |
| US-20210309600-A1 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2021-10-07 | — | — | US | disclosed |
| US-11046636-B2 | Polymerizable absorbers of UV and high energy visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2021-06-29 | — | — | US | disclosed |
| CN-112334444-A | Polymerizable absorbers for UV and high energy visible light | 强生视力健公司 | 2021-02-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11970431-B2 | Polymerizable absorbers of UV and high energy visible light | F12, RAD54L, RAD51 | PKM 279/4885HTT 1768/4885LMNA 1318/4885 |
| US-11046636-B2 | Polymerizable absorbers of UV and high energy visible light | F12, IK, RAD51 | PKM 308/4885HTT 1939/4885LMNA 1117/4885 |
| US-20210309600-A1 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | F12, RAD54L, RAD51 | PKM 279/4885HTT 1768/4885LMNA 1318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.