Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | DBH | P09172 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29033636 | 0.82 | PKM (0.75) | PKMTDP1POLBKDM4ECTDSP1 | |
| SCHEMBL30498916 | 0.82 | PKM (0.75) | PKMTDP1POLBKDM4ECTDSP1 | |
| SCHEMBL10741391 | 0.80 | TDP1 (0.64) | PKMTDP1POLBKDM4ECTDSP1 | |
| SCHEMBL9573894 | 0.79 | KDM4E (0.53) | PKMTDP1POLBKDM4EMAPT | |
| SCHEMBL16689315 | 0.78 | PKM (0.57) | PKMTDP1POLBKDM4ECTDSP1 | |
| SCHEMBL16689297 | 0.78 | PKM (0.57) | PKMTDP1POLBKDM4ECTDSP1 | |
| SCHEMBL23549385 | 0.78 | PKM (0.60) | PKMTDP1POLBKDM4ECTDSP1 | |
| SCHEMBL30662204 | 0.78 | PKM (0.60) | PKMTDP1POLBKDM4ECTDSP1 | |
| SCHEMBL5962841 | 0.77 | PKM (0.58) | PKMTDP1POLBKDM4ECTDSP1 | |
| SCHEMBL27748861 | 0.76 | TDP1 (0.62) | PKMTDP1POLBKDM4ECTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170099837-A1 | EXTRACTS OF AGRICULTURAL HUSKS USED TO MODIFY THE METABOLISM OF PLANTS | MEDINA ESQUER LUIS ROMAN (MX) | 2017-04-13 | — | — | US | disclosed |
| US-20170099837-A1 | EXTRACTS OF AGRICULTURAL HUSKS USED TO MODIFY THE METABOLISM OF PLANTS | MEDINA ESQUER LUIS ROMAN (MX) | 2017-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170099837-A1 | EXTRACTS OF AGRICULTURAL HUSKS USED TO MODIFY THE METABOLISM OF PLANTS | PCK1, SNRK, HPD | PKM 132/4885TDP1 2424/4885POLB 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.