Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.49 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL298493 | 1.00 | HIF1A (0.56) | HIF1ACHRNA7TRAP1ALDH1A1CYP1A2 | |
| Iodide SCHEMBL5085194 | 1.00 | HIF1A (0.56) | HIF1ACHRNA7TRAP1ALDH1A1CYP1A2 | |
| Iodide SCHEMBL2505241 | 1.00 | HIF1A (0.56) | HIF1ACHRNA7TRAP1ALDH1A1CYP1A2 | |
| Iodide SCHEMBL10684637 | 1.00 | HIF1A (0.56) | HIF1ACHRNA7TRAP1ALDH1A1CYP1A2 | |
| Iodide SCHEMBL3859955 | 1.00 | HIF1A (0.56) | HIF1ACHRNA7TRAP1ALDH1A1CYP1A2 | |
| Iodide SCHEMBL6904643 | 1.00 | HIF1A (0.56) | HIF1ACHRNA7TRAP1ALDH1A1CYP1A2 | |
| Decyltriphenylphosphonium SCHEMBL3654788 | 1.00 | HIF1A (0.56) | HIF1ACHRNA7TRAP1ALDH1A1CYP1A2 | |
| Iodide SCHEMBL5085133 | 1.00 | HIF1A (0.56) | HIF1ACHRNA7TRAP1ALDH1A1CYP1A2 | |
| Iodide SCHEMBL5091833 | 1.00 | HIF1A (0.56) | HIF1ACHRNA7TRAP1ALDH1A1CYP1A2 | |
| Iodide SCHEMBL5086696 | 1.00 | HIF1A (0.56) | HIF1ACHRNA7TRAP1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115417769-A | Method for synthesizing sex pheromone component of tomato leaf miner and intermediate | 昆明博鸿科技有限公司 | 2022-12-02 | — | — | CN | claimed |
| US-9238606-B1 | Methyl-Iodide-free carbonylation of methanol to acetaldehyde | EASTMAN CHEMICAL COMPANY (US) | 2016-01-19 | — | — | US | claimed |
| WO-2025095106-A1 | RESIST UNDERLAYER FILM FORMATION COMPOSITION | 日産化学株式会社 | 2025-05-08 | — | — | WO | disclosed |
| CN-114746468-B | Method for producing polymer | 日产化学株式会社 | 2024-09-13 | — | — | CN | disclosed |
| US-11701373-B2 | Substituted bicyclic compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-07-18 | — | — | US | disclosed |
| US-20230103242-A1 | METHOD FOR PRODUCING POLYMER | NISSAN CHEMICAL CORPORATION (JP) | 2023-03-30 | — | — | US | disclosed |
| US-20230029997-A1 | COMPOSITION FOR FORMING RESIST UNDERLAYER FILM | NISSAN CHEMICAL CORPORATION (JP) | 2023-02-02 | — | — | US | disclosed |
| CN-115417769-A | Method for synthesizing sex pheromone component of tomato leaf miner and intermediate | 昆明博鸿科技有限公司 | 2022-12-02 | — | — | CN | disclosed |
| US-20220331346-A1 | SUBSTITUTED BICYCLIC COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2022-10-20 | — | — | US | disclosed |
| CN-114761876-A | Composition for forming resist underlayer film | 日产化学株式会社 | 2022-07-15 | — | — | CN | disclosed |
| CN-114746468-A | Method for producing polymer | 日产化学株式会社 | 2022-07-12 | — | — | CN | disclosed |
| EP-0518973-B1 | ISOMERIZATION OF EPOXYALKENES TO 2,5-DIHYDROFURANS AND CATALYSTS COMPOSITIONS USEFUL THEREFOR | EASTMAN CHEM CO (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0624157-A1 | CONTINUOUS PROCESS FOR THE MANUFACTURE OF 2,5-DIHYDROFURANS FROM -g(g),-g(d)-EPOXYBUTENES. | EASTMAN CHEM CO (US) | 1994-11-17 | — | — | EP | disclosed |
| US-5315019-A | Continuous process for the manufacture of 2,5-dihydrofurans from γ, δ-epoxybutenes | EASTMAN CHEMICAL COMPANY (US) | 1994-05-24 | — | — | US | disclosed |
| WO-1993010111-A1 | CONTINUOUS PROCESS FOR THE MANUFACTURE OF 2,5-DIHYDROFURANS FROM η,δ-EPOXYBUTENES | EASTMAN KODAK COMPANY (US) | 1993-05-27 | — | — | WO | disclosed |
| EP-0518973-A1 | ISOMERIZATION OF EPOXYALKENES TO 2,5-DIHYDROFURANS AND CATALYSTS COMPOSITIONS USEFUL THEREFOR. | EASTMAN KODAK CO (US) | 1992-12-23 | — | — | EP | disclosed |
| US-5082956-A | Quaternary onium iodide catalyst | EASTMAN KODAK COMPANY (US) | 1992-01-21 | — | — | US | disclosed |
| CN-1055359-A | Isomery epoxy alkene is 2,5-dihydrofuran and its useful catalysts composition | EASTMAN KODAK CO (US) | 1991-10-16 | — | — | CN | disclosed |
| WO-1991013882-A1 | ISOMERIZATION OF EPOXYALKENES TO 2,5-DIHYDROFURANS AND CATALYSTS COMPOSITIONS USEFUL THEREFOR | EASTMAN KODAK COMPANY (US) | 1991-09-19 | — | — | WO | disclosed |
| US-4027040-A | ANALGESICS | ROUSSEL-UCLAF (FR) | 1977-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220331346-A1 | SUBSTITUTED BICYCLIC COMPOUNDS | S1PR1, S1PR3, S1PR2 | HIF1A 2605/4885CHRNA7 694/4885TRAP1 3324/4885 |
| US-11701373-B2 | Substituted bicyclic compounds | S1PR1, S1PR3, S1PR2 | HIF1A 2605/4885CHRNA7 694/4885TRAP1 3324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.