SCHEMBL2354992

SCHEMBL2354992

OCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC(O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.40
ALDH1A1 P00352 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TSHR P16473 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.35
GPR84 Q9NQS5 1/20 0.35
FFAR1 O14842 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
TRPV1 Q8NER1 1/20 0.33
THRB P10828 1/20 0.33
TRPA1 O75762 1/20 0.33
PTPN1 P18031 1/20 0.32
CYP2D6 P10635 2/20 0.31
SPHK1 Q9NYA1 1/20 0.31
GMNN O75496 1/20 0.31
POLB P06746 1/20 0.31
THPO P40225 1/20 0.31
MTOR P42345 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12537757 1.00 LMNA (0.40) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL136026 1.00
SCHEMBL29041550 1.00 LMNA (0.40) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL1132272 1.00 LMNA (0.40) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL16516576 1.00 LMNA (0.40) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL70845 1.00 LMNA (0.40) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL10777196 1.00 LMNA (0.40) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL570305 1.00 LMNA (0.40) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL343041 1.00 LMNA (0.40) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL6607224 1.00 LMNA (0.40) LMNAALDH1A1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8830811-B2 Resin composition and optical component MITSUI CHEMICALS, INC. (JP) 2014-09-09 US disclosed
CN-103122076-A Resin composition and molded article produced from the composition MITSUI CHEMICALS INC 2013-05-29 CN disclosed
EP-1878769-B1 RESIN COMPOSITION AND OPTICAL COMPONENT MITSUI CHEMICALS INC (JP) 2013-04-17 EP disclosed
CN-101522813-B Resin composition and molded article obtained from the composition MITSU CHEMICALS INC 2013-01-30 CN disclosed
US-20120277355-A1 RESIN COMPOSITION AND USE THEREOF MITSUI CHEMICALS, INC. (JP) 2012-11-01 US disclosed
EP-1842645-B1 PROCESS FOR PRODUCING CYCLOOLEFIN RESIN COMPOSITION MITSUI CHEMICALS INC (JP) 2011-08-24 EP disclosed
CN-101160358-B Resin composition and optical component MITSUI CHEMICALS INC 2011-08-24 CN disclosed
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION MITSUI CHEMICALS, INC. (JP) 2010-03-25 US disclosed
US-7674413-B2 Process for producing cycloolefin resin composition MITSUI CHEMICALS, INC. (JP) 2010-03-09 US disclosed
US-20090310471-A1 Resin composition and optical component MITSUI CHEMICALS, INC. (JP) 2009-12-17 US disclosed
EP-1767576-B1 RESIN COMPOSITION AND USE THEREOF MITSUI CHEMICALS INC (JP) 2009-12-02 EP disclosed
CN-101522813-A Resin composition and molded article obtained from the composition MITSUI CHEMICALS INC (JP) 2009-09-02 CN disclosed
US-20080304393-A1 Resin Composition And Use Thereof MITSUI CHEMICALS, INC. 2008-12-11 US disclosed
CN-101160358-A Resin composition and optical component MITSUI CHEMICALS INC (JP) 2008-04-09 CN disclosed
EP-1878769-A1 RESIN COMPOSITION AND OPTICAL COMPONENT Mitsui Chemicals, Inc. (JP) 2008-01-16 EP disclosed
US-20070299199-A1 Process for Producing Cycloolefin Resin Composition MITSUI CHEMICALS, INC. (JP) 2007-12-27 US disclosed
EP-1842645-A1 PROCESS FOR PRODUCING CYCLOOLEFIN RESIN COMPOSITION Mitsui Chemicals, Inc. (JP) 2007-10-10 EP disclosed
EP-1767576-A1 RESIN COMPOSITION AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2007-03-28 EP disclosed
EP-1081194-A1 THERMOPLASTIC RESIN COMPOSITION AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2001-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION SEM1, WDR5, WDR1 LMNA 2153/4885ALDH1A1 1728/4885HSD17B10 4686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.