Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30498963 | 0.77 | SMN1; SMN2 (0.55) | NPC1TP53SMN1; SMN2TSHRRAB9A | |
| SCHEMBL11013773 | 0.77 | SMN1; SMN2 (0.55) | NPC1TP53SMN1; SMN2TSHRRAB9A | |
| SCHEMBL23550595 | 0.76 | MAPT (0.47) | NPC1TP53SMN1; SMN2TSHRRAB9A | |
| SCHEMBL756109 | 0.74 | PIK3CD (0.41) | NPC1TP53SMN1; SMN2TSHRRAB9A | |
| SCHEMBL23550098 | 0.73 | RXFP1 (0.56) | NPC1TP53SMN1; SMN2TSHRRAB9A | |
| SCHEMBL16331977 | 0.73 | NT5E (0.59) | NPC1TP53SMN1; SMN2TSHRMET | |
| SCHEMBL15013527 | 0.72 | NPC1 (0.49) | NPC1TP53SMN1; SMN2TSHRRAB9A | |
| SCHEMBL30242943 | 0.70 | NPC1 (1.00) | NPC1TP53SMN1; SMN2TSHRRAB9A | |
| SCHEMBL2474693 | 0.70 | NPC1 (1.00) | NPC1TP53SMN1; SMN2TSHRRAB9A | |
| SCHEMBL17841547 | 0.70 | NPC1 (0.54) | NPC1TP53SMN1; SMN2TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188889-A1 | PLATINUM COMPOUNDS FOR BINDING GUANINE QUADRUPLEXES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188889-A1 | PLATINUM COMPOUNDS FOR BINDING GUANINE QUADRUPLEXES | PCNA, DDB1, SERBP1 | NPC1 4133/4885TP53 64/4885SMN1; SMN2 1432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.