Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | NPY2R | P49146 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | LDHB | P07195 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23551479 | 0.91 | L3MBTL1 (0.40) | L3MBTL1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23551391 | 0.90 | LMNA (0.41) | L3MBTL1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31334108 | 0.85 | MAPT (0.38) | L3MBTL1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL23551473 | 0.85 | FFAR4 (0.41) | L3MBTL1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL29744638 | 0.84 | MAPT (0.38) | L3MBTL1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29535010 | 0.84 | MAPT (0.42) | L3MBTL1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL23539031 | 0.84 | MAPT (0.38) | L3MBTL1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23538815 | 0.84 | MAPT (0.42) | L3MBTL1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL25122064 | 0.83 | MAPT (0.39) | L3MBTL1NPC1RAB9ASMN1; SMN2LMNA | |
| Lithium SCHEMBL29946900 | 0.83 | MAPT (0.41) | L3MBTL1KDM4ENPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127561-A1 | ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR | C4 THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |