SCHEMBL23551663

SCHEMBL23551663

CN1CC=C(c2ccc(N)c(F)c2)CC1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
QDPR P09417 3/20 0.57
SLC6A4 P31645 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19107632 0.83 QDPR (0.59) QDPR
SCHEMBL22642944 0.83 QDPR (0.59) QDPR
SCHEMBL22821272 0.82 QDPR (0.57) QDPRSLC6A4
SCHEMBL8345083 0.81 QDPR (0.54) QDPR
SCHEMBL19155163 0.79 QDPR (0.55) QDPRSLC6A4
SCHEMBL16003507 0.79 QDPR (0.71) QDPRSLC6A4
SCHEMBL155267 0.79 QDPR (0.68) QDPRSLC6A4
SCHEMBL1814323 0.79 QDPR (0.68) QDPR
SCHEMBL27979395 0.78 MEN1 (0.42) QDPR
SCHEMBL23316338 0.77 QDPR (0.56) QDPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021127561-A1 ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR C4 THERAPEUTICS, INC. (US) 2021-06-24 WO disclosed