Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926368 | 0.83 | SIGMAR1 (0.39) | MMP2MMP3 | |
| SCHEMBL23551663 | 0.81 | QDPR (0.57) | QDPR | |
| SCHEMBL19107632 | 0.80 | QDPR (0.59) | QDPRHTR1DHTR1B | |
| SCHEMBL3503819 | 0.77 | QDPR (0.51) | QDPRHTR1DHTR1B | |
| SCHEMBL8915112 | 0.77 | QDPR (0.62) | QDPR | |
| SCHEMBL27195861 | 0.76 | QDPR (0.50) | QDPRMMP2MMP3 | |
| SCHEMBL8344859 | 0.76 | QDPR (0.49) | QDPRMMP2MMP3 | |
| SCHEMBL16003507 | 0.76 | QDPR (0.71) | QDPR | |
| SCHEMBL1814323 | 0.75 | QDPR (0.68) | QDPR | |
| SCHEMBL10638336 | 0.74 | HTR2C (0.54) | QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |