Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2363443 | 0.85 | CHRM5 (0.34) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL4299694 | 0.74 | LMNA (0.52) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL7161305 | 0.73 | SLC25A20 (0.34) | LMNAMAPTFABP3MAPK1MEN1 | |
| Bromide SCHEMBL1782654 | 0.72 | TSHR (0.49) | LMNAADRA1AMAPTSMN1; SMN2BLM | |
| SCHEMBL25398870 | 0.71 | SMN1; SMN2 (0.39) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL9067782 | 0.70 | TSHR (0.42) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL4965117 | 0.69 | CYP3A4 (0.55) | CYP3A4 | |
| SCHEMBL27991507 | 0.68 | TSHR (0.36) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL15158309 | 0.68 | LMNA (0.59) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL6666152 | 0.68 | FABP3 (0.52) | LMNAESR1ADORA3CDC25AAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846010-B1 | EXTERNAL SKIN AGENT COMPRISING MODIFIED CLAY FOR PREVENTING INFLAMMATION | POLA CHEM IND INC (JP) | 2011-08-03 | — | — | EP | claimed |