Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CDC25A | P30304 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15158309 | 0.85 | LMNA (0.59) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL3524266 | 0.83 | SMN1; SMN2 (0.48) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL5527468 | 0.82 | LMNA (0.47) | LMNAESR1ADORA3CDC25AAGTR1 | |
| Ethylene Glycol SCHEMBL15862264 | 0.79 | SMN1; SMN2 (0.48) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL5475887 | 0.78 | LMNA (0.66) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL1643920 | 0.78 | LMNA (0.66) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL14990456 | 0.77 | LMNA (0.64) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL3923049 | 0.77 | LMNA (0.64) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL3502011 | 0.76 | SMN1; SMN2 (0.45) | LMNAESR1ADORA3CDC25AAGTR1 | |
| Hydrochloric Acid SCHEMBL7058592 | 0.76 | TSHR (0.51) | LMNAADRA1AMAPTSMN1; SMN2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090304765-A1 | R-RAS ACTIVITY IN VASCULAR REGULATION | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-12-10 | — | — | US | disclosed |
| EP-1976547-A1 | R-RAS ACTIVITY IN VASCULAR REGULATION | Vascular Biosciences (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007055561-A1 | R-RAS ACTIVITY IN VASCULAR REGULATION | VASCULAR BIOSCIENCES (US) | 2007-05-18 | — | — | WO | disclosed |