Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23552087 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CYP2C9THRBCYP2C19HSD17B10 | |
| SCHEMBL23551743 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CYP2C9THRBCYP2C19HSD17B10 | |
| SCHEMBL3596338 | 0.85 | ALDH1A1 (0.57) | ALDH1A1CYP2C9THRBCYP2C19HSD17B10 | |
| SCHEMBL23552106 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP2C9THRBCYP2C19HSD17B10 | |
| SCHEMBL23552058 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP2C9THRBCYP2C19HSD17B10 | |
| SCHEMBL13386048 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP2C9THRBCYP2C19HSD17B10 | |
| Hydrochloric Acid SCHEMBL23525225 | 0.82 | ALDH1A1 (0.49) | ALDH1A1CYP2C9THRBCYP2C19HSD17B10 | |
| Hydrochloric Acid SCHEMBL23525493 | 0.82 | ALDH1A1 (0.49) | ALDH1A1CYP2C9THRBCYP2C19HSD17B10 | |
| Hydrochloric Acid SCHEMBL23525226 | 0.82 | ALDH1A1 (0.49) | ALDH1A1CYP2C9THRBCYP2C19HSD17B10 | |
| Hydrochloric Acid SCHEMBL23525229 | 0.82 | ALDH1A1 (0.49) | ALDH1A1CYP2C9THRBCYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188906-A1 | TUBULYSIN ANALOGUES AS ANTICANCER AGENTS AND PAYLOADS FOR ANTIBODY-DRUG CONJUGATES AND METHODS OF TREATMENT THEREWITH | WILLIAM MARSH RICE UNIVERSITY (US) | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188906-A1 | TUBULYSIN ANALOGUES AS ANTICANCER AGENTS AND PAYLOADS FOR ANTIBODY-DRUG CONJUGATES AND METHODS OF TREATMENT THEREWITH | TEK, CD2BP2, SDCBP | ALDH1A1 3809/4885CYP2C9 4812/4885THRB 1824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.