Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22245676 | 1.00 | TSHR (0.37) | TSHRALDH1A1CHRM1AKR1A1CHRM3 | |
| SCHEMBL10609028 | 0.82 | TSHR (0.40) | TSHRALDH1A1CHRM1AKR1A1CHRM3 | |
| SCHEMBL10609026 | 0.82 | TSHR (0.40) | TSHRALDH1A1CHRM1AKR1A1CHRM3 | |
| SCHEMBL10609023 | 0.82 | TSHR (0.40) | TSHRALDH1A1CHRM1AKR1A1CHRM3 | |
| SCHEMBL2415232 | 0.81 | — | — | |
| SCHEMBL18263281 | 0.80 | ADRA1A (0.41) | TSHRALDH1A1CHRM1AKR1A1CHRM3 | |
| SCHEMBL28248434 | 0.80 | TSHR (0.39) | TSHRALDH1A1CHRM1AKR1A1CHRM3 | |
| SCHEMBL18263279 | 0.80 | ADRA1A (0.41) | TSHRALDH1A1CHRM1AKR1A1CHRM3 | |
| SCHEMBL18271781 | 0.80 | TSHR (0.39) | TSHRALDH1A1CHRM1AKR1A1CHRM3 | |
| SCHEMBL27805132 | 0.80 | ADRA1A (0.41) | TSHRALDH1A1CHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12365649-B2 | Process for the preparation of brivaracetam | ALIVUS LIFE SCIENCES LIMITED (IN) | 2025-07-22 | — | — | US | disclosed |
| US-20240010618-A1 | PROCESS FOR THE PREPARATION OF BRIVARACETAM | ALIVUS LIFE SCIENCES LIMITED (IN) | 2024-01-11 | — | — | US | disclosed |
| CN-106748748-B | Preparation method and intermediate of brivaracetam | 成都国为生物医药有限公司 | 2021-08-24 | — | — | CN | disclosed |
| WO-2021124066-A1 | PROCESS FOR THE PREPARATION OF BRIVARACETAM | GLENMARK LIFE SCIENCES LIMITED (IN) | 2021-06-24 | — | — | WO | disclosed |
| CN-106748748-A | A kind of Preparation Method And Their Intermediate of Bu Waxitan | 成都国弘医药有限公司 | 2017-05-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12365649-B2 | Process for the preparation of brivaracetam | CYP2C19, CYP2B6, POR | TSHR 865/4885ALDH1A1 1369/4885CHRM1 224/4885 |
| US-20240010618-A1 | PROCESS FOR THE PREPARATION OF BRIVARACETAM | CYP2C19, CYP2B6, POR | TSHR 865/4885ALDH1A1 1369/4885CHRM1 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.