Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609026 | 1.00 | TSHR (0.40) | TSHRALDH1A1TDP1CHRM1AKR1A1 | |
| SCHEMBL10609023 | 1.00 | TSHR (0.40) | TSHRALDH1A1TDP1CHRM1AKR1A1 | |
| SCHEMBL9176709 | 0.86 | ALDH1A1 (0.52) | TSHRALDH1A1TDP1TP53CA2 | |
| SCHEMBL10578855 | 0.86 | ALDH1A1 (0.52) | TSHRALDH1A1TDP1TP53CA2 | |
| SCHEMBL6172192 | 0.85 | — | — | |
| SCHEMBL28248434 | 0.84 | TSHR (0.39) | TSHRALDH1A1TDP1CHRM1AKR1A1 | |
| SCHEMBL18271781 | 0.84 | TSHR (0.39) | TSHRALDH1A1TDP1CHRM1AKR1A1 | |
| SCHEMBL38661702 | 0.83 | ALDH1A1 (0.48) | TSHRALDH1A1TDP1TP53CA2 | |
| SCHEMBL23552104 | 0.82 | TSHR (0.37) | TSHRALDH1A1TDP1CHRM1AKR1A1 | |
| SCHEMBL22245676 | 0.82 | TSHR (0.37) | TSHRALDH1A1TDP1CHRM1AKR1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227306-B1 | PEPTIDE IMMUNOSTIMULANTS | PFIZER INC. (US) | 1989-09-13 | — | — | EP | disclosed |
| US-4767743-A | ANTIINFECTION AGENTS | PFIZER INC. (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0227306-A2 | Peptide immunostimulants | PFIZER INC. (US) | 1987-07-01 | — | — | EP | disclosed |