SCHEMBL2355451

SCHEMBL2355451

C[Si](C)(C)CCOCCO

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
MAPK1 P28482 1/20 0.56
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
ALDH1A1 P00352 1/20 0.46
THRB P10828 1/20 0.41
HTT P42858 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL430949 0.85
SCHEMBL10608124 0.84 TSHR (0.54) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL29430863 0.82 TSHR (0.52) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL419805 0.82 MEN1 (0.32) MEN1KMT2A
SCHEMBL1289421 0.82 MEN1 (0.32) MEN1KMT2A
SCHEMBL28175 0.80
SCHEMBL14827640 0.76 MEN1 (0.58) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL6856328 0.75
Di(Hydroxyethyl)Ether SCHEMBL27549537 0.75
Di(Hydroxyethyl)Ether SCHEMBL2410410 0.74 TSHR (1.00) TSHRMAPK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230193067-A1 METAL OXIDE COMPOSITION, LIGHT-EMITTING DEVICE USING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20180120702-A1 TETRACARBOXYLIC ACID DIESTER COMPOUND, POLYMER OF POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING SAME, NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING PROCESS, AND METHOD FOR FORMING CURED FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-05-03 US disclosed
EP-3268353-A1 PYRAZOLYL-DERIVATIVES AS PEST CONTROL AGENTS Bayer Animal Health GmbH (DE) 2018-01-17 EP disclosed
EP-3157913-A1 PYRAZOLYL-TRIAZOLYL-PYRIDINES AS PEST-CONTROL AGENTS Bayer Animal Health GmbH (DE) 2017-04-26 EP disclosed
EP-3089972-A1 NOVEL PYRAZOLYL-HETEROARYLAMIDES AS PESTICIDES Bayer Animal Health GmbH (DE) 2016-11-09 EP disclosed
WO-2016142394-A1 PYRAZOLYL-DERIVATIVES AS PEST CONTROL AGENTS BAYER ANIMAL HEALTH GMBH (DE) 2016-09-15 WO disclosed
EP-2964632-A1 NOVEL HALOGEN-SUBSTITUTED COMPOUNDS Bayer CropScience Aktiengesellschaft (DE) 2016-01-13 EP disclosed
EP-2964631-A1 NOVEL HALOGEN-SUBSTITUTED COMPOUNDS Bayer Animal Health GmbH (DE) 2016-01-13 EP disclosed
WO-2015193216-A1 PYRAZOLYL-TRIAZOLYL-PYRIDINES AS PEST-CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2015-12-23 WO disclosed
EP-2953942-A1 HALOGEN-SUBSTITUTED PYRAZOL DERIVATIVES AS PEST-CONTROL AGENTS Bayer CropScience Aktiengesellschaft (DE) 2015-12-16 EP disclosed
EP-2686303-A1 N-(3-CARBAMOYLPHENYL)-1H-PYRAZOLE-5-CARBOXAMIDE DERIVATIVES AND THE USE THEREOF FOR CONTROLLING ANIMAL PESTS Bayer Intellectual Property GmbH (DE) 2014-01-22 EP disclosed
WO-2013092522-A1 NOVEL INSECTICIDAL AROMATIC AMIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-06-27 WO disclosed
WO-2012126766-A1 N-(3-CARBAMOYLPHENYL)-1H-PYRAZOLE-5-CARBOXAMIDE DERIVATIVES AND THE USE THEREOF FOR CONTROLLING ANIMAL PESTS BAYER CROPSCIENCE AG (DE) 2012-09-27 WO disclosed
EP-2352723-A2 HALOGEN-SUBSTITUTED COMPOUNDS USED AS PESTICIDES Bayer CropScience AG (DE) 2011-08-10 EP disclosed
WO-2010051926-A2 NEW HALOGEN-SUBSTITUTED BONDS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-05-14 WO disclosed
WO-2009141096-A1 SUBSTITUTED SPIRO-ISOXAZOLINES BAYER CROPSCIENCE AG (DE) 2009-11-26 WO disclosed
EP-2054427-A2 AVERMECTIN DERIVATIVES Bayer CropScience AG (DE) 2009-05-06 EP disclosed
WO-2008019784-A2 AVERMECTIN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2008-02-21 WO disclosed
EP-1412346-A1 METHOD FOR PRODUCING NOVEL SPINOSYN DERIVATIVES Bayer CropScience AG (DE) 2004-04-28 EP disclosed
WO-2003010155-A1 METHOD FOR PRODUCING NOVEL SPINOSYN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2003-02-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180120702-A1 TETRACARBOXYLIC ACID DIESTER COMPOUND, POLYMER OF POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING SAME, NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING PROCESS, AND METHOD FOR FORMING CURED FILM TET1, KDM1A, KDM2B TSHR 3618/4885MAPK1 1628/4885MEN1 1695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.