⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12455815 | 0.83 | ALOX15 (0.35) | — | |
| SCHEMBL29767921 | 0.81 | — | — | |
| SCHEMBL430949 | 0.81 | — | — | |
| SCHEMBL2355451 | 0.80 | TSHR (0.56) | — | |
| SCHEMBL419805 | 0.78 | MEN1 (0.32) | — | |
| SCHEMBL1289421 | 0.78 | MEN1 (0.32) | — | |
| SCHEMBL7738612 | 0.74 | — | — | |
| SCHEMBL292853 | 0.73 | — | — | |
| SCHEMBL431029 | 0.73 | — | — | |
| SCHEMBL7737998 | 0.72 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 460 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029226-A1 | METHOD FOR THE SYNTHESIS OF CHIRAL ALPHA-ARYL PROPIONIC ACID DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2012-02-02 | — | — | US | claimed |
| EP-2049689-B1 | NUCLEIC ACID AMPLIFICATION USING A REVERSIBLY MODIFIED OLIGONUCLEOTIDE | BI WANLI (US) | 2011-12-21 | — | — | EP | claimed |
| EP-2393771-A1 | Method for the synthesis of chiral alpha-aryl propionic acid derivatives | DSM IP Assets B.V. (NL) | 2011-12-14 | — | — | EP | claimed |
| EP-1979362-B1 | NOVEL SILANE COMPOUNDS AND USE THEREOF IN ORDER TO FUNCTIONALISE SOLID MEDIA AND IMMOBILISE BIOLOGICAL MOLECULES ON SAID MEDIA | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2010-12-15 | — | — | EP | claimed |
| WO-2010089343-A1 | METHOD FOR THE SYNTHESIS OF CHIRAL ALPHA-ARYL PROPIONIC ACID DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2010-08-12 | — | — | WO | claimed |
| EP-1979362-A1 | NOVEL SILANE COMPOUNDS AND USE THEREOF IN ORDER TO FUNCTIONALISE SOLID MEDIA AND IMMOBILISE BIOLOGICAL MOLECULES ON SAID MEDIA | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-10-15 | — | — | EP | claimed |
| WO-2007088186-A1 | NOVEL SILANE COMPOUNDS AND USE THEREOF IN ORDER TO FUNCTIONALISE SOLID MEDIA AND IMMOBILISE BIOLOGICAL MOLECULES ON SAID MEDIA | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2007-08-09 | — | — | WO | claimed |
| US-7022860-B2 | Tricyclic triazolobenzazepine derivatives, process for producing the same, and antiallergic agents | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-04-04 | — | — | US | claimed |
| EP-0650484-B1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2000-01-26 | — | — | EP | claimed |
| JP-3106894-A | — | — | None | — | — | JP | disclosed |
| CN-121586712-A | Novel compounds | 豪夫迈·罗氏有限公司 | 2026-02-27 | — | — | CN | disclosed |
| WO-2025026882-A1 | NOVEL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-02-06 | — | — | WO | disclosed |
| US-20240228502-A1 | 2-PHENYLAMINO PYRROLOPYRIMIDINES AS ACK1 INHIBITORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-07-11 | — | — | US | disclosed |
| US-20240182622-A1 | BLOCK COPOLYMERS, MEMBRANES, AND METHODS | The Florida State University Research Foundation, Inc. | 2024-06-06 | — | — | US | disclosed |
| EP-0515232-A1 | 2-benzocoumarinyl-carbapenems | MERCK & CO. INC. (US) | 1992-11-25 | — | — | EP | disclosed |
| US-5104982-A | ROUTE TO GLYCALS IN THE ALLAL AND GULAL SERIES | YALE UNIVERSITY (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0448412-A2 | A route to glycals in the allal and gulal series | YALE UNIVERSITY (US) | 1991-09-25 | — | — | EP | disclosed |
| EP-0444208-A1 | LIPID A MONOSACCHARIDE ANALOG | Japan Tobacco Inc. (JP) | 1991-09-04 | — | — | EP | disclosed |
| JP-H03106894-A | LIPID A MONOSACCHARIDE ANALOG | JAPAN TOBACCO INC | 1991-05-07 | — | — | JP | disclosed |
| EP-0337920-A2 | Process for high regioselective esterification and ether-cleavage on unsaturated sugar compounds with the help of lipases and esterases and products obtained with that process | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-18 | — | — | EP | disclosed |