Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUT7 | Q11130 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609576 | 0.98 | FUT7 (0.49) | FUT7CA2SMN1; SMN2LMNAHTT | |
| SCHEMBL10609457 | 0.95 | CA2 (0.43) | FUT7CA2SMN1; SMN2LMNAHTT | |
| SCHEMBL10606942 | 0.87 | ALDH1A1 (0.40) | CA2SMN1; SMN2CA1CA9ALDH1A1 | |
| SCHEMBL9420098 | 0.81 | FUT7 (0.52) | FUT7CA2SMN1; SMN2LMNAHTT | |
| SCHEMBL11868694 | 0.81 | FUT7 (0.49) | FUT7CA2SMN1; SMN2LMNAHTT | |
| SCHEMBL9927244 | 0.81 | FUT7 (0.49) | FUT7CA2SMN1; SMN2LMNAHTT | |
| SCHEMBL11711323 | 0.81 | FUT7 (0.56) | FUT7CA2SMN1; SMN2LMNAHTT | |
| SCHEMBL981061 | 0.80 | CA2 (0.68) | CA2SMN1; SMN2LMNAHTTCA1 | |
| Calcium SCHEMBL9420103 | 0.80 | FUT7 (0.48) | FUT7CA2SMN1; SMN2LMNAHTT | |
| Ammonia Solution, Strong SCHEMBL9420050 | 0.80 | FUT7 (0.48) | FUT7CA2SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |