SCHEMBL23555331

SCHEMBL23555331

CCCC(CC)(CCC)c1ncc[nH]1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP19A1 P11511 2/20 0.35
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TXN P10599 1/20 0.32
TXNRD1 Q16881 1/20 0.32
HTR1A P08908 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL366680 0.81 CYP19A1 (0.39) ALDH1A1SMN1; SMN2CYP19A1CYP1A2CYP3A4
SCHEMBL11306595 0.79 CYP19A1 (0.39) ALDH1A1SMN1; SMN2CYP19A1CYP1A2CYP3A4
SCHEMBL3700407 0.78 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2CYP19A1CYP1A2CYP3A4
SCHEMBL29749649 0.75 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2CYP19A1CYP1A2CYP3A4
SCHEMBL13493243 0.74 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2CYP19A1CYP1A2CYP3A4
SCHEMBL3707615 0.74 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2CYP19A1CYP1A2CYP3A4
SCHEMBL25627105 0.73 CYP19A1 (0.37) ALDH1A1SMN1; SMN2CYP19A1CYP1A2CYP3A4
SCHEMBL27951250 0.72 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2CYP19A1CYP1A2CYP3A4
SCHEMBL3695170 0.72 CYP19A1 (0.39) ALDH1A1SMN1; SMN2CYP19A1CYP1A2CYP3A4
SCHEMBL27922362 0.70 CYP19A1 (0.38) ALDH1A1SMN1; SMN2CYP19A1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021124279-A1 COMPOUNDS ACTIVE TOWARDS NUCLEAR RECEPTORS NUEVOLUTION A/S (DK) 2021-06-24 WO disclosed