Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | TXN | P10599 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3700407 | 0.83 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2CYP19A1TXNTXNRD1 | |
| SCHEMBL13493243 | 0.83 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2CYP19A1TXNTXNRD1 | |
| SCHEMBL9459967 | 0.81 | CYP19A1 (0.41) | ALDH1A1SMN1; SMN2CYP19A1TXNTXNRD1 | |
| SCHEMBL3695170 | 0.80 | CYP19A1 (0.39) | ALDH1A1SMN1; SMN2CYP19A1TXNTXNRD1 | |
| SCHEMBL29749649 | 0.80 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2CYP19A1TXNTXNRD1 | |
| SCHEMBL27922362 | 0.79 | CYP19A1 (0.38) | ALDH1A1SMN1; SMN2CYP19A1TXNTXNRD1 | |
| SCHEMBL5500827 | 0.78 | CYP19A1 (0.39) | ALDH1A1SMN1; SMN2CYP19A1FDPS | |
| SCHEMBL22059382 | 0.77 | CYP19A1 (0.37) | ALDH1A1SMN1; SMN2CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL27951250 | 0.77 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2CYP19A1TXNTXNRD1 | |
| SCHEMBL67017 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103361630-A | Group 2 imidazolate formulations for direct liquid injection | AIR PROD & CHEM | 2013-10-23 | — | — | CN | claimed |
| WO-2022007966-A1 | PB2 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川海思科制药有限公司 | 2022-01-13 | — | — | WO | disclosed |
| US-10968215-B2 | Pyrido five-element aromatic ring compound, preparation method therefor and use thereof | SHANGHAI HAIHE PHARMACEUTICAL CO., LTD. (CN) | 2021-04-06 | — | — | US | disclosed |
| US-9884828-B2 | Substituted cinnolines as inhibitors of LRRK2 kinase activity | IMAGO PHARMACEUTICALS, INC. (US) | 2018-02-06 | — | — | US | disclosed |
| US-9873680-B2 | Therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2018-01-23 | — | — | US | disclosed |
| WO-2016033243-A9 | ANTIRETROVIRAL AGENTS | GILEAD SCIENCES, INC. (US) | 2016-05-19 | — | — | WO | disclosed |
| US-9018387-B2 | Complexes of imidazole ligands | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2015-04-28 | — | — | US | disclosed |
| US-8680289-B2 | Complexes of imidazole ligands | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| CN-103361630-A | Group 2 imidazolate formulations for direct liquid injection | AIR PROD & CHEM | 2013-10-23 | — | — | CN | disclosed |
| EP-2580223-A1 | COMPLEXES OF IMIDAZOLE LIGANDS | Air Products and Chemicals, Inc. (US) | 2013-04-17 | — | — | EP | disclosed |
| US-20130078391-A1 | Complexes Of Imidazole Ligands | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2013-03-28 | — | — | US | disclosed |
| US-20120276051-A1 | INHIBITORS OF HEPATITIS C VIRUS | PRESIDIO PHARMACEUTICALS, INC. (US) | 2012-11-01 | — | — | US | disclosed |
| US-20120121806-A1 | Complexes Of Imidazole Ligands | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2012-05-17 | — | — | US | disclosed |
| CN-102344413-A | Volatile imidazoles and group 2 imidazole based metal precursors | AIR PROD & CHEM | 2012-02-08 | — | — | CN | disclosed |
| WO-2011156699-A1 | COMPLEXES OF IMIDAZOLE LIGANDS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2011-12-15 | — | — | WO | disclosed |
| WO-2008116339-A2 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120276051-A1 | INHIBITORS OF HEPATITIS C VIRUS | HAVCR2, LIPC, HCCS | ALDH1A1 1654/4885SMN1; SMN2 4681/4885CYP19A1 3232/4885 |
| US-20130078391-A1 | Complexes Of Imidazole Ligands | ICOSLG, CLTC, PICALM | ALDH1A1 4464/4885SMN1; SMN2 4415/4885CYP19A1 4833/4885 |
| US-10968215-B2 | Pyrido five-element aromatic ring compound, preparation method therefor and use thereof | EZH2, IKZF2, SUZ12 | ALDH1A1 2816/4885SMN1; SMN2 4308/4885CYP19A1 937/4885 |
| US-20120121806-A1 | Complexes Of Imidazole Ligands | ICOSLG, CLTC, PICALM | ALDH1A1 4464/4885SMN1; SMN2 4415/4885CYP19A1 4833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.