SCHEMBL23555405

SCHEMBL23555405

c1cc2ccc(-c3cc4cc5sc(-c6ccc7ccsc7c6)cc5cc4s3)cc2s1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.44
ESR2 Q92731 9/20 0.44
DYRK1A Q13627 1/20 0.39
APP P05067 2/20 0.36
SIGMAR1 Q99720 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23555664 0.93 ESR1 (0.46) ESR1ESR2DYRK1AAPPSIGMAR1
SCHEMBL25165785 0.90 ESR1 (0.44) ESR1ESR2DYRK1AAPPSIGMAR1
SCHEMBL23556013 0.89 ESR1 (0.52) ESR1ESR2DYRK1AAPP
SCHEMBL20625217 0.87 DYRK1A (0.53) ESR1ESR2DYRK1AAPP
SCHEMBL23556016 0.87 ESR1 (0.50) ESR1ESR2DYRK1AAPP
SCHEMBL23556012 0.87 ESR1 (0.50) ESR1ESR2DYRK1AAPP
SCHEMBL25061031 0.84 APP (0.56) ESR1ESR2DYRK1AAPP
SCHEMBL18711160 0.84 APP (0.44) ESR1ESR2DYRK1AAPP
SCHEMBL29981744 0.84 ESR1 (0.38) ESR1ESR2DYRK1AAPP
SCHEMBL148089 0.82 DYRK1A (0.40) ESR1ESR2DYRK1AAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11770974-B2 P active materials for organic photoelectric conversion layers in organic photodiodes SONY CORPORATION (JP) 2023-09-26 US disclosed
US-11770974-B2 P active materials for organic photoelectric conversion layers in organic photodiodes SONY CORPORATION (JP) 2023-09-26 US disclosed
US-20210193935-A1 P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES SONY CORPORATION (JP) 2021-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11770974-B2 P active materials for organic photoelectric conversion layers in organic photodiodes JUP, L1CAM, EPCAM ESR1 560/4885ESR2 1872/4885DYRK1A 3505/4885
US-20210193935-A1 P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES JUP, L1CAM, EPCAM ESR1 560/4885ESR2 1872/4885DYRK1A 3505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.