Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1782333 | 0.92 | MEN1 (0.44) | MEN1CYP3A4ALOX15KMT2APTPN1 | |
| SCHEMBL1785187 | 0.89 | MEN1 (0.42) | MEN1CYP3A4ALOX15KMT2APTPN1 | |
| SCHEMBL1780624 | 0.83 | MEN1 (0.37) | MEN1CYP3A4ALOX15KMT2APTPN1 | |
| SCHEMBL5201000 | 0.82 | MEN1 (0.60) | MEN1CYP3A4ALOX15KMT2APTPN1 | |
| SCHEMBL10340685 | 0.82 | MEN1 (0.60) | MEN1CYP3A4ALOX15KMT2APTPN1 | |
| SCHEMBL1783553 | 0.82 | MEN1 (0.37) | MEN1CYP3A4ALOX15KMT2APTPN1 | |
| SCHEMBL16074981 | 0.80 | MEN1 (0.58) | MEN1CYP3A4ALOX15KMT2APTPN1 | |
| SCHEMBL11700396 | 0.80 | LMNA (0.61) | MEN1CYP3A4ALOX15KMT2APTPN1 | |
| SCHEMBL12999684 | 0.79 | MEN1 (0.56) | MEN1CYP3A4ALOX15KMT2APTPN1 | |
| SCHEMBL14047326 | 0.79 | MEN1 (0.56) | MEN1CYP3A4ALOX15KMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536690-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | Arizona Board Of Regents (US) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011103536-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | ARIZONA BOARD OF REGENTS (US) | 2011-08-25 | — | — | WO | disclosed |