Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | APEX1 | P27695 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395599 | 0.85 | MAPT (0.74) | MAPTALDH1A1TDP1ALOX15LMNA | |
| SCHEMBL19830567 | 0.85 | MAPT (0.74) | MAPTALDH1A1TDP1ALOX15LMNA | |
| SCHEMBL5342481 | 0.82 | MAPT (0.70) | MAPTALDH1A1TDP1ALOX15LMNA | |
| SCHEMBL9041537 | 0.82 | MAPT (0.81) | MAPTALDH1A1TDP1ALOX15LMNA | |
| SCHEMBL25471518 | 0.81 | MAPT (0.68) | MAPTALDH1A1TDP1ALOX15LMNA | |
| Avobenzone SCHEMBL15650 | 0.81 | ALDH1A1 (1.00) | MAPTALDH1A1TDP1ALOX15LMNA | |
| Avobenzone SCHEMBL1768910 | 0.81 | ALDH1A1 (1.00) | MAPTALDH1A1TDP1ALOX15LMNA | |
| SCHEMBL9403511 | 0.81 | MAPT (0.68) | MAPTALDH1A1TDP1ALOX15LMNA | |
| SCHEMBL22241270 | 0.81 | ALDH1A1 (0.81) | MAPTALDH1A1TDP1ALOX15LMNA | |
| SCHEMBL78643 | 0.80 | MAPT (0.64) | MAPTALDH1A1TDP1ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635777-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GmbH (DE) | 2006-03-22 | — | — | EP | claimed |
| WO-2004105712-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2004-12-09 | — | — | WO | claimed |
| EP-2350182-A1 | METHOD OF QUENCHING ELECTRONIC EXCITATION OF CHROMOPHORE-CONTAINING ORGANIC MOLECULES IN PHOTOACTIVE COMPOSITIONS | HallStar Innovations Corp. (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010051103-A1 | METHOD OF QUENCHING ELECTRONIC EXCITATION OF CHROMOPHORE-CONTAINING ORGANIC MOLECULES IN PHOTOACTIVE COMPOSITIONS | HALLSTAR INNOVATIONS CORP. (US) | 2010-05-06 | — | — | WO | disclosed |