SCHEMBL395599

SCHEMBL395599

COc1ccc(C(=O)c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.74
ALDH1A1 P00352 4/20 0.72
LMNA P02545 3/20 0.72
MAPK1 P28482 2/20 0.72
ALOX15 P16050 1/20 0.72
APEX1 P27695 1/20 0.72
RECQL P46063 1/20 0.72
HSD17B10 Q99714 1/20 0.72
TDP1 Q9NUW8 1/20 0.72
SRD5A2 P31213 1/20 0.63
MEN1 O00255 2/20 0.62
RAB9A P51151 2/20 0.62
KMT2A Q03164 2/20 0.62
NPC1 O15118 1/20 0.62
EPHX2 P34913 1/20 0.62
NR1H4 Q96RI1 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
NPSR1 Q6W5P4 1/20 0.61
RXFP1 Q9HBX9 1/20 0.61
HPGD P15428 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19830567 1.00 MAPT (0.74) MAPTALDH1A1LMNAMAPK1ALOX15
SCHEMBL25471518 0.95 MAPT (0.68) MAPTALDH1A1LMNAMAPK1ALOX15
SCHEMBL5075015 0.87 MAPT (0.58) MAPTALDH1A1LMNAMAPK1ALOX15
SCHEMBL18627186 0.87 MAPT (0.58) MAPTALDH1A1LMNAMAPK1ALOX15
SCHEMBL26999140 0.86 SRD5A2 (0.66) MAPTALDH1A1LMNAMAPK1ALOX15
SCHEMBL19339948 0.86 SRD5A2 (0.66) MAPTALDH1A1LMNAMAPK1ALOX15
SCHEMBL1148445 0.85 SRD5A2 (0.83) MAPTALDH1A1LMNATDP1SRD5A2
SCHEMBL10946728 0.85 SRD5A2 (0.83) MAPTALDH1A1LMNATDP1SRD5A2
SCHEMBL9418310 0.85 RXFP1 (0.79) MAPTALDH1A1LMNAMAPK1MEN1
SCHEMBL51509 0.85 RXFP1 (0.79) MAPTALDH1A1LMNAMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113314402-B Photoresist composition and method for manufacturing semiconductor device 台湾积体电路制造股份有限公司 2025-03-25 CN disclosed
CN-113311661-B Photoresist underlayer composition and method for manufacturing semiconductor device 台湾积体电路制造股份有限公司 2024-10-15 CN disclosed
CN-116573994-B Direct cross-coupling method of triazine ester and aryl bromide 南京工业大学 2024-06-14 CN disclosed
CN-116573994-A Direct cross-coupling method of triazine ester and aryl bromide 南京工业大学 2023-08-11 CN disclosed
WO-2018077967-A1 FLUOROPOLYMER LAMINATE FOR THERMOFORMING INTO VEHICLES BODY PANELS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2018-05-03 WO disclosed
US-8101211-B2 Controlling moisture, elasticity of skin; using plant extracts; antiinflammatory agents; antiallergens KABUSHIKI KAISHA YAKULT HONSHA (JP) 2012-01-24 US disclosed
US-20040028643-A1 Compositions for retarding skin aging KABUSHIKI KAISHA YAKULT HONSHA (JP) 2004-02-12 US disclosed
EP-1352640-A1 COMPOSITIONS FOR RETARDING SKIN AGING Kabushiki Kaisha Yakult Honsha (JP) 2003-10-15 EP disclosed
US-6476024-B1 Pyridazine derivatives and related composition SHISEIDO CO. LTD. (JP) 2002-11-05 US disclosed
EP-0860433-B1 QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME KIRIN BREWERY (JP) 2002-07-03 EP disclosed
US-6143764-A ETHER DERIVATIVES OF QUINOLINE, ANTITUMOR AGENTS KIRIN BEER KABUSHIKI KAISHA (JP) 2000-11-07 US disclosed
EP-0860433-A1 QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME KIRIN BEER KABUSHIKI KAISHA (JP) 1998-08-26 EP disclosed
US-4115413-A ACID FREE BAYER AKTIENGESELLSCHAFT (DE) 1978-09-19 US disclosed