Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3802450 | 0.88 | KIF11 (0.34) | KIF11EGFRAKR1C3AKR1C2NPC1 | |
| SCHEMBL30656907 | 0.88 | KIF11 (0.34) | KIF11EGFRAKR1C3AKR1C2NPC1 | |
| SCHEMBL28209977 | 0.85 | KIF11 (0.33) | KIF11LMNATYRSLC6A2HDAC1 | |
| SCHEMBL29852649 | 0.84 | SLC6A2 (0.33) | KIF11EGFRAKR1C3AKR1C2NPC1 | |
| SCHEMBL562077 | 0.84 | SLC6A2 (0.33) | KIF11EGFRAKR1C3AKR1C2NPC1 | |
| SCHEMBL1160379 | 0.81 | NPC1 (0.33) | NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL31377054 | 0.78 | EGFR (0.37) | KIF11EGFRAKR1C3AKR1C2NPC1 | |
| SCHEMBL562692 | 0.77 | KIF11 (0.33) | KIF11LMNATYRSLC6A2HDAC1 | |
| SCHEMBL562252 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL14837113 | 0.72 | EGFR (0.33) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008384-B2 | Liquid butylaryl phosphite compositions | CHEMTURA CORPORATION (US) | 2011-08-30 | — | — | US | disclosed |
| US-20100190900-A1 | LIQUID BUTYLARYL PHOSPHITE COMPOSITIONS | CHEMTURA CORPORATION (US) | 2010-07-29 | — | — | US | disclosed |