Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23524119 | 0.87 | GRIA1 (0.53) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| SCHEMBL30355544 | 0.87 | GRIA1 (0.53) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| SCHEMBL30355642 | 0.78 | CYP11B1 (0.70) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| SCHEMBL23524034 | 0.78 | CYP11B1 (0.70) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| SCHEMBL23524427 | 0.72 | MAPT (0.46) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| SCHEMBL23558362 | 0.70 | MAPT (0.51) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| SCHEMBL13606307 | 0.70 | CASP3 (0.77) | CYP2C9CYP2C19CASP3SENP8SENP7 | |
| SCHEMBL30355778 | 0.70 | S1PR1 (0.43) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| SCHEMBL23524097 | 0.70 | S1PR1 (0.43) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| SCHEMBL3306566 | 0.69 | KIF11 (0.69) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188826-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | TREVENA, INC. | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188826-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | S1PR1, S1PR2, S1PR3 | CYP11B1 1869/4885CYP11B2 2298/4885CYP2C9 4770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.