SCHEMBL23558663

SCHEMBL23558663

c1ccc2c(c1)OC1(O2)C2CC3CC(C2)CC1C3

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 6/20 0.37
ALOX12 P18054 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.32
ITGB2 P05107 1/20 0.32
ICAM1 P05362 1/20 0.32
ITGAL P20701 1/20 0.32
BRD4 O60885 1/20 0.30
CREBBP Q92793 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23558664 0.77 HSD11B1 (0.36) HSD11B1BRD4CREBBPHTR2CHTR2B
SCHEMBL31178066 0.71 HSD11B1 (0.39) HSD11B1ALOX12HTR2C
SCHEMBL7098420 0.70 HTR2C (0.45) HSD11B1HTR2CHTR2B
SCHEMBL23333433 0.69 CHRM3 (0.36) HSD11B1ALOX12
SCHEMBL18815082 0.68 ALOX12 (0.30) ALOX12
SCHEMBL18814832 0.68 ALOX12 (0.30) ALOX12
SCHEMBL13182547 0.67 CYP3A4 (0.37) HSD11B1ALOX12
SCHEMBL8321738 0.67 TSHR (0.33)
SCHEMBL18788896 0.67
SCHEMBL14021449 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11675267-B2 Resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-06-13 US disclosed
US-11675267-B2 Resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-06-13 US disclosed
US-20210191266-A1 RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN, AND COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-06-24 US disclosed