Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.40 |
| ▸ | MMP2 | P08253 | 4/20 | 0.38 |
| ▸ | MMP3 | P08254 | 4/20 | 0.38 |
| ▸ | MMP9 | P14780 | 4/20 | 0.38 |
| ▸ | MMP8 | P22894 | 4/20 | 0.38 |
| ▸ | MMP12 | P39900 | 4/20 | 0.38 |
| ▸ | MMP13 | P45452 | 4/20 | 0.38 |
| ▸ | MMP14 | P50281 | 4/20 | 0.38 |
| ▸ | MMP16 | P51512 | 4/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14432862 | 1.00 | CNR1 (0.40) | CNR1MMP2MMP3MMP9MMP8 | |
| SCHEMBL1995866 | 0.89 | ABCB11 (0.46) | CNR1MMP2MMP3MMP9MMP8 | |
| SCHEMBL2356020 | 0.81 | MMP2 (0.40) | CNR1MMP2MMP3MMP9MMP8 | |
| SCHEMBL14432860 | 0.81 | CTSA (0.43) | CNR1MMP2MMP3MMP9MMP8 | |
| SCHEMBL1991394 | 0.79 | ABCB11 (0.38) | MMP2MMP3MMP9MMP13ABCB11 | |
| SCHEMBL14432859 | 0.79 | FFAR4 (0.40) | CNR1MMP2MMP3MMP9MMP8 | |
| SCHEMBL1992062 | 0.79 | ABCB11 (0.49) | MMP2MMP3MMP9MMP8MMP12 | |
| SCHEMBL2356023 | 0.79 | MMP2 (0.39) | CNR1MMP2MMP3MMP9MMP8 | |
| SCHEMBL14432857 | 0.79 | MMP2 (0.39) | CNR1MMP2MMP3MMP9MMP8 | |
| SCHEMBL1988973 | 0.77 | PTGDR2 (0.41) | ABCB11PTGDR2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008350-B2 | Biphenyloxyacetic acid derivatives for the treatment of respiratory disease | ASTRAZENECA AB (SE) | 2011-08-30 | — | — | US | disclosed |