Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.53 |
| ▸ | RET | P07949 | 16/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20046342 | 0.87 | RET (0.53) | GPR119RET | |
| SCHEMBL28576085 | 0.87 | NR1H2 (0.54) | GPR119RET | |
| SCHEMBL23561119 | 0.86 | RET (0.54) | GPR119RET | |
| SCHEMBL29421852 | 0.82 | CKS1B (0.51) | GPR119RET | |
| SCHEMBL25309158 | 0.82 | SMO (0.54) | GPR119RET | |
| SCHEMBL2142161 | 0.82 | CKS1B (0.51) | GPR119RET | |
| SCHEMBL17978916 | 0.82 | CKS1B (0.51) | GPR119RET | |
| SCHEMBL14938608 | 0.82 | MAP4K4 (0.52) | GPR119RET | |
| SCHEMBL28981151 | 0.81 | CKS1B (0.48) | GPR119RET | |
| SCHEMBL25209887 | 0.80 | GPR119 (0.49) | GPR119RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192989-A2 | PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS | AZKARRA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2021123291-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |