Sugi Predict

Sugi Predict / Compounds / SCHEMBL28981151

SCHEMBL28981151

SCHEMBL28981151

C#Cc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ncc1C

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CKS1B P61024 2/20 0.48
▸ SKP1 P63208 2/20 0.48
▸ SKP2 Q13309 2/20 0.48
▸ RET P07949 13/20 0.47
▸ GPR119 Q8TDV5 4/20 0.46
▸ MAP4K4 O95819 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28981148 0.85 CKS1B (0.46) CKS1BSKP1SKP2RETGPR119
SCHEMBL28981154 0.82 CKS1B (0.51) CKS1BSKP1SKP2RETGPR119
SCHEMBL31129873 0.82 MAP4K4 (0.52) CKS1BSKP1SKP2RETGPR119
SCHEMBL23560773 0.81 GPR119 (0.53) RETGPR119
SCHEMBL14938608 0.80 MAP4K4 (0.52) CKS1BSKP1SKP2RETGPR119
SCHEMBL29421852 0.80 CKS1B (0.51) CKS1BSKP1SKP2RETGPR119
SCHEMBL25309158 0.80 SMO (0.54) CKS1BSKP1SKP2RETGPR119
SCHEMBL17978916 0.80 CKS1B (0.51) CKS1BSKP1SKP2RETGPR119
SCHEMBL2142161 0.80 CKS1B (0.51) CKS1BSKP1SKP2RETGPR119
SCHEMBL5916431 0.79 ADK (0.56) CKS1BSKP1SKP2RETGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115772170-B Pyrazolo [1,5-a ] pyridine derivative and preparation method and application thereof 徐诺药业(南京)有限公司 2025-05-16 — — CN disclosed
CN-115772170-A Pyrazolo [1,5-a ] pyridine derivative and preparation method and application thereof 徐诺药业(南京)有限公司 2023-03-10 — — CN disclosed
Send feedback