Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL962304 | 0.71 | BRD4 (0.43) | KDM4EMAPTMEN1KMT2AALOX15 | |
| SCHEMBL29102194 | 0.70 | KDM4E (0.40) | KDM4EMAPTMEN1KMT2AALOX15 | |
| SCHEMBL14535333 | 0.69 | — | — | |
| SCHEMBL9797391 | 0.68 | KDM4E (0.48) | KDM4EMAPTMEN1KMT2AALOX15 | |
| SCHEMBL4191233 | 0.68 | KMT2A (0.41) | KDM4EMAPTMEN1KMT2AALOX15 | |
| SCHEMBL24287193 | 0.67 | POLB (0.42) | KDM4EMAPTMEN1KMT2AALOX15 | |
| SCHEMBL11295836 | 0.66 | OPRM1 (0.42) | KDM4EMAPTMEN1KMT2AALOX15 | |
| SCHEMBL4448027 | 0.66 | KMT2A (0.42) | KDM4EMAPTMEN1KMT2AALOX15 | |
| SCHEMBL22397156 | 0.66 | KMT2A (0.42) | KDM4EMAPTMEN1KMT2AALOX15 | |
| SCHEMBL10743660 | 0.66 | KDM4E (0.43) | KDM4EMAPTMEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021121396-A1 | TRICYCLIC COMPOUND THAT ACTS AS PLASMA KALLIKREIN INHIBITOR AND USE THEREOF | 成都康弘药业集团股份有限公司 | 2021-06-24 | — | — | WO | disclosed |