Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | UNG | P13051 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192215 | 0.84 | ALDH1A1 (0.53) | TP53SMN1; SMN2CYP3A4MEN1KMT2A | |
| SCHEMBL3130397 | 0.84 | TP53 (0.50) | TP53TDP1SMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL232779 | 0.82 | TP53 (0.64) | TP53TDP1SMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL29944162 | 0.82 | CYP3A4 (0.65) | TP53TDP1SMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL132541 | 0.82 | CYP3A4 (0.65) | TP53TDP1SMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL28557809 | 0.81 | TP53 (0.55) | TP53TDP1SMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL2559515 | 0.81 | ERN1 (0.49) | TP53TDP1SMN1; SMN2CYP3A4MEN1 | |
| Hydrochloric Acid SCHEMBL2299193 | 0.81 | TP53 (0.62) | TP53TDP1SMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL9133420 | 0.81 | TP53 (0.62) | TP53TDP1SMN1; SMN2CYP3A4MEN1 | |
| Hydrochloric Acid SCHEMBL3088495 | 0.81 | TP53 (0.62) | TP53TDP1SMN1; SMN2CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3405477-B1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| WO-2021127214-A1 | SYNTHETIC PROCESSES AND INTERMEDIATES | ARBUTUS BIOPHARMA CORPORATION (CA) | 2021-06-24 | — | — | WO | disclosed |