Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | ESR1 | P03372 | 9/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465985 | 1.00 | LMNA (0.61) | LMNAHSD17B10ESR1SMN1; SMN2PGR | |
| SCHEMBL7885573 | 1.00 | LMNA (0.61) | LMNAHSD17B10ESR1SMN1; SMN2PGR | |
| SCHEMBL6468428 | 1.00 | LMNA (0.61) | LMNAHSD17B10ESR1SMN1; SMN2PGR | |
| SCHEMBL10800294 | 0.90 | LMNA (0.61) | LMNAHSD17B10ESR1SMN1; SMN2PGR | |
| SCHEMBL6463118 | 0.87 | LMNA (0.46) | LMNAHSD17B10ESR1SMN1; SMN2PGR | |
| SCHEMBL5353798 | 0.87 | LMNA (0.58) | LMNAHSD17B10ESR1SMN1; SMN2PGR | |
| SCHEMBL14559142 | 0.87 | LMNA (0.58) | LMNAHSD17B10ESR1SMN1; SMN2PGR | |
| SCHEMBL6466047 | 0.86 | LMNA (0.45) | LMNAHSD17B10ESR1SMN1; SMN2PGR | |
| SCHEMBL6853652 | 0.85 | LMNA (0.46) | LMNAHSD17B10ESR1SMN1; SMN2PGR | |
| SCHEMBL6465178 | 0.85 | LMNA (0.44) | LMNAHSD17B10ESR1SMN1; SMN2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350111-A1 | PROCESSES AND INTERMEDIATES FOR THE PRODUCTION OF FULVESTRANT | Synthon B.V. (NL) | 2011-08-03 | — | — | EP | disclosed |
| US-20100105934-A1 | FULVESTRANT INTERMEDIATE | SYNTHON BV (NL) | 2010-04-29 | — | — | US | disclosed |
| WO-2010043404-A1 | PROCESSES AND INTERMEDIATES FOR THE PRODUCTION OF FULVESTRANT | SYNTHON B.V. (NL) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105934-A1 | FULVESTRANT INTERMEDIATE | CYP19A1, NR5A1, HSD17B11 | LMNA 2929/4885HSD17B10 141/4885ESR1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.