Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24534978 | 0.84 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL23564893 | 0.83 | DGAT1 (0.33) | DGAT1ALDH1A1 | |
| SCHEMBL23525109 | 0.72 | — | — | |
| SCHEMBL6892470 | 0.71 | ADORA1 (0.38) | DGAT1KDM4EALDH1A1HPGD | |
| SCHEMBL30975943 | 0.70 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL31412670 | 0.69 | DGAT1 (0.36) | DGAT1KDM4EALDH1A1HPGD | |
| SCHEMBL24534977 | 0.69 | DGAT1 (0.33) | DGAT1ALDH1A1 | |
| SCHEMBL24906231 | 0.69 | DGAT1 (0.39) | DGAT1ALDH1A1HPGD | |
| SCHEMBL30975918 | 0.69 | DGAT1 (0.35) | DGAT1KDM4EALDH1A1HPGD | |
| SCHEMBL23567652 | 0.68 | AURKA (0.38) | KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11661419-B2 | Benzimidazole derivative compounds and uses thereof | PFIZER INC. (US) | 2023-05-30 | — | — | US | disclosed |
| WO-2022130175-A1 | PYRIDO[2,3-D]IMIDAZOLE DERIVATIVES AND THEIR USE AS INHIBITORS OF ITK FOR THE TEATMENT OF SKIN DISEASE | PFIZER INC. (US) | 2022-06-23 | — | — | WO | disclosed |
| US-20210188829-A1 | Chemical Compounds | PFIZER INC. (US) | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11661419-B2 | Benzimidazole derivative compounds and uses thereof | ITK, HRH4, BLK | DGAT1 4107/4885KDM4E 1222/4885ALDH1A1 242/4885 |
| US-20210188829-A1 | Chemical Compounds | ITK, HRH4, HRH1 | DGAT1 3972/4885KDM4E 1327/4885ALDH1A1 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.