Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24534977 | 0.84 | DGAT1 (0.33) | DGAT1ALDH1A1MAPT | |
| SCHEMBL23564892 | 0.83 | DGAT1 (0.34) | DGAT1ALDH1A1 | |
| SCHEMBL23564869 | 0.82 | DGAT1 (0.32) | DGAT1ALDH1A1MAPT | |
| SCHEMBL24535030 | 0.82 | DGAT1 (0.32) | DGAT1ALDH1A1MAPT | |
| SCHEMBL26198238 | 0.75 | DGAT1 (0.34) | DGAT1ALDH1A1MAPT | |
| SCHEMBL25344152 | 0.75 | DGAT1 (0.34) | DGAT1ALDH1A1MAPT | |
| SCHEMBL16534131 | 0.74 | DGAT1 (0.33) | DGAT1ALDH1A1 | |
| SCHEMBL15564073 | 0.74 | DGAT1 (0.30) | DGAT1ALDH1A1MAPT | |
| SCHEMBL22615382 | 0.73 | MEN1 (0.33) | DGAT1ALDH1A1 | |
| SCHEMBL23524989 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11661419-B2 | Benzimidazole derivative compounds and uses thereof | PFIZER INC. (US) | 2023-05-30 | — | — | US | disclosed |
| US-20210188829-A1 | Chemical Compounds | PFIZER INC. (US) | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11661419-B2 | Benzimidazole derivative compounds and uses thereof | ITK, HRH4, BLK | DGAT1 4107/4885ALDH1A1 242/4885MAPT 2297/4885 |
| US-20210188829-A1 | Chemical Compounds | ITK, HRH4, HRH1 | DGAT1 3972/4885ALDH1A1 167/4885MAPT 1663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.