Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12017799 | 0.78 | GAA (0.43) | MAPTCYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL12788677 | 0.75 | SLC22A12 (0.40) | HTR7MAPTCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL12017843 | 0.75 | ATM (0.40) | HTR7MAPTCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL19446092 | 0.75 | ATM (0.37) | ADRA2AMAPTCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL18386511 | 0.74 | ABL1 (0.43) | ADRA2A | |
| SCHEMBL11454653 | 0.73 | HTR7 (0.36) | HTR7MAPTCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL11709263 | 0.73 | HTR7 (0.33) | ADRA2AHTR7MAPTCYP1A2CYP3A4 | |
| SCHEMBL11446387 | 0.73 | HTR7 (0.36) | HTR7MAPTCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL17700237 | 0.73 | SLC22A12 (0.41) | HTR7MAPTCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL20934953 | 0.71 | RAB9A (0.50) | MAPTCYP1A2CYP2D6CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021121420-A1 | BENZOPYRAZOLE COMPOUND AND INTERMEDIATE, PREPARATION METHOD, AND APPLICATION THEREOF | 江苏凯迪恩医药科技有限公司 | 2021-06-24 | — | — | WO | disclosed |