Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23566418 | 0.89 | KDM4E (0.51) | DHODHMEN1KMT2AHTTRAB9A | |
| SCHEMBL4669212 | 0.86 | DHODH (0.51) | DHODHMEN1KMT2AHTTRAB9A | |
| SCHEMBL28099069 | 0.81 | KDM4E (0.50) | DHODHMEN1KMT2AHTTRAB9A | |
| SCHEMBL23566408 | 0.80 | MAPK1 (0.52) | DHODHHTTRAB9ALMNAALDH1A1 | |
| SCHEMBL7837545 | 0.78 | DHODH (0.49) | DHODHMEN1KMT2AHTTRAB9A | |
| SCHEMBL23566381 | 0.78 | CTSS (0.48) | DHODHMEN1KMT2AHTTRAB9A | |
| SCHEMBL23566383 | 0.78 | CTSS (0.48) | DHODHMEN1KMT2AHTTRAB9A | |
| SCHEMBL16767712 | 0.77 | NAMPT (0.45) | MEN1KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL23976267 | 0.77 | GAA (0.56) | MEN1KMT2AHTTRAB9ANPC1 | |
| SCHEMBL23566389 | 0.77 | CTSS (0.53) | MEN1KMT2AHTTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362436-B1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | UNIV ANTWERPEN (BE) | 2021-06-30 | — | — | EP | disclosed |