Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23566402 | 0.89 | DHODH (0.44) | L3MBTL1MEN1HTTKMT2ADHODH | |
| SCHEMBL28099069 | 0.85 | KDM4E (0.50) | KDM4EL3MBTL1TDP1MEN1HTT | |
| SCHEMBL4669212 | 0.85 | DHODH (0.51) | KDM4EL3MBTL1TDP1MEN1HTT | |
| SCHEMBL12472332 | 0.83 | KDM4E (0.47) | KDM4EL3MBTL1TDP1MEN1HTT | |
| SCHEMBL12472466 | 0.81 | KDM4E (0.47) | KDM4EL3MBTL1TDP1MEN1HTT | |
| SCHEMBL23566400 | 0.79 | SIRT5 (0.49) | KDM4ETDP1MEN1KMT2APOLB | |
| SCHEMBL31569082 | 0.79 | KDM4E (0.43) | KDM4EL3MBTL1TDP1MEN1HTT | |
| SCHEMBL3146288 | 0.79 | GAA (0.54) | KDM4EL3MBTL1TDP1HTTPOLB | |
| SCHEMBL12472879 | 0.78 | KDM4E (0.46) | KDM4EL3MBTL1TDP1MEN1HTT | |
| SCHEMBL2550727 | 0.78 | KDM4E (0.44) | KDM4EL3MBTL1TDP1POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362436-B1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | UNIV ANTWERPEN (BE) | 2021-06-30 | — | — | EP | disclosed |