Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23566950 | 0.79 | EPHX2 (0.40) | NAAAEPHX2EPHX1SMN1; SMN2 | |
| SCHEMBL23323338 | 0.79 | EPHX2 (0.40) | NAAAEPHX2EPHX1SMN1; SMN2 | |
| SCHEMBL23323337 | 0.79 | EPHX2 (0.40) | NAAAEPHX2EPHX1SMN1; SMN2 | |
| SCHEMBL23552243 | 0.79 | EPHX2 (0.40) | NAAAEPHX2EPHX1SMN1; SMN2 | |
| SCHEMBL18811280 | 0.79 | TSHR (0.45) | EPHX2SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL11252838 | 0.74 | NAAA (0.62) | NAAAEPHX2EPHX1SMN1; SMN2HTT | |
| SCHEMBL11170145 | 0.74 | NAAA (0.56) | NAAAEPHX1SMN1; SMN2HTTCYP2C19 | |
| SCHEMBL24366798 | 0.73 | NAAA (0.62) | NAAAEPHX2EPHX1SMN1; SMN2HTT | |
| SCHEMBL18681693 | 0.72 | NAAA (0.73) | NAAAEPHX1HTTALDH1A1 | |
| SCHEMBL22996788 | 0.72 | NAAA (0.52) | NAAAEPHX2EPHX1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150392-A1 | INTRANASAL ADMINISTRATION OF N-ACETYLCYSTEINE AND USES THEREOF | Neuronasal, Inc. (US) | 2023-08-10 | — | — | WO | disclosed |
| WO-2021127541-A1 | METHODS OF TREATING BRAIN DISORDERS | Neuronasal, Inc. (US) | 2021-06-24 | — | — | WO | disclosed |