Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963579 | 0.74 | EPHX2 (0.56) | MAPTEPHX2HTTTDP1CTSK | |
| SCHEMBL3172394 | 0.70 | EPHX2 (0.54) | MAPTEPHX2HTTTDP1KMT2A | |
| SCHEMBL17182799 | 0.67 | DPP7 (0.52) | MAPTKMT2ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL3175750 | 0.66 | EPHX2 (0.56) | MAPTEPHX2HTTTDP1KMT2A | |
| SCHEMBL8980476 | 0.65 | HTT (0.63) | MAPTHTTTDP1KMT2ASMN1; SMN2 | |
| SCHEMBL6627421 | 0.65 | TSHR (0.42) | MAPTEPHX2TDP1CTSKSMN1; SMN2 | |
| SCHEMBL812289 | 0.65 | MAPT (0.45) | MAPTEPHX2CTSKKMT2ASMN1; SMN2 | |
| SCHEMBL7827049 | 0.65 | MAPT (0.45) | MAPTEPHX2HTTKMT2ASMN1; SMN2 | |
| SCHEMBL5964054 | 0.65 | EPHX2 (0.54) | MAPTEPHX2HTTTDP1KMT2A | |
| SCHEMBL8586015 | 0.64 | ALDH1A1 (0.52) | MAPTEPHX2HTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842430-B1 | SET8 LYSINE METHYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | HAINAN YILING MEDICAL IND & DEVELOPMENT CO LTD (CN) | 2022-09-28 | — | — | EP | disclosed |
| US-20210363138-A1 | SET8 LYSINE METHYLTRANSFERASE INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF | HAINAN YILING MEDICAL INDUSTRY & DEVELOPMENT Co., Ltd. (CN) | 2021-11-25 | — | — | US | disclosed |
| EP-3842430-A1 | SET8 LYSINE METHYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | Hainan Yiling Medical Industry & Development Co. Ltd (CN) | 2021-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210363138-A1 | SET8 LYSINE METHYLTRANSFERASE INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF | SETDB1, SETD7, SETD1A | MAPT 2171/4885EPHX2 2972/4885HTT 4654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.